Aghahosseini Farzaneh, Ghasemzadeh Hoseini Elaheh, Mahdavi Nazanin
Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Oral and Maxillofacial Medicine, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Front Dent. 2022 Jan 15;19:3. doi: 10.18502/fid.v19i3.8511. eCollection 2022.
Actinomycosis is caused by Actinomyces species and is relatively rare in humans. Because of the special collateral blood flow, osteomyelitis is less common in the maxilla than the mandible. Although there are few case reports for jaw osteomyelitis, actinomycotic osteomyelitis associated with phenytoin therapy has not been reported before. The data show that antiepileptic drugs induce suppression of the immune system. This report presents a rare case of a 58-year-old man on phenytoin with actinomycotic osteomyelitis, and reviews the relevant literature.
放线菌病由放线菌属引起，在人类中相对罕见。由于特殊的侧支血流情况，上颌骨骨髓炎比下颌骨骨髓炎少见。虽然颌骨骨髓炎的病例报告较少，但此前尚未有苯妥英治疗相关的放线菌性骨髓炎的报告。数据显示抗癫痫药物会导致免疫系统受到抑制。本报告介绍了一例罕见的58岁男性患者，其因苯妥英治疗而患放线菌性骨髓炎，并对相关文献进行了综述。
