Nishiwaki H, Satake K, Ko I, Tanaka H, Kanazawa G, Nagai Y, Umeyama K
Nihon Geka Gakkai Zasshi. 1986 Nov;87(11):1443-8.
Measurements of pancreatic microflow were investigated using hydrogen gas generated by electrolysis in dog. After laparatomy under general anesthesia, uncinate process of the pancreas was punctured by a needle electrode for electrolysis and determination of hydrogen gas. The consecutive measurements of pancreatic microflow revealed the good reproducibility at the same point of the pancreas. The simultaneous measurements of pancreatic microflow by electrolysis and pancreatic tissue blood flow by H2 inhalation method were carried out at the same point of the pancreas. Correlation analysis of both measurements revealed coefficient of 0.751 and a significant relationship was observed (p less than 0.05). However, the value was a little higher in pancreatic microflow as compared with pancreatic tissue blood flow. Pancreatic microflow and pancreatic exocrine secretion increased after intravenous administration of Dopamine and Secretin (10 micrograms/kg/min). It is concluded that the measurement of pancreatic microflow by hydrogen gas generated by electrolysis is a useful method on understanding the microcirculation of the pancreas.
在犬身上，利用电解产生的氢气对胰腺微血流进行了测量研究。在全身麻醉下进行剖腹手术后，用针电极穿刺胰腺钩突进行电解并测定氢气。胰腺微血流的连续测量显示在胰腺的同一点具有良好的可重复性。在胰腺的同一点同时用电解法测量胰腺微血流和用氢气吸入法测量胰腺组织血流量。两种测量方法的相关性分析显示系数为0.751，且观察到显著关系（p小于0.05）。然而，与胰腺组织血流量相比，胰腺微血流的值略高。静脉注射多巴胺和促胰液素（10微克/千克/分钟）后，胰腺微血流和胰腺外分泌增加。得出结论：用电解产生的氢气测量胰腺微血流是了解胰腺微循环的一种有用方法。
