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通过标准化的缺血性前臂试验改善劳力性肌痛的筛查。

Improvement of screening in exertional myalgia with a standardized ischemic forearm test.

作者信息

Sinkeler S P, Wevers R A, Joosten E M, Binkhorst R A, Oei L T, Van't Hof M A, De Haan A F

出版信息

Muscle Nerve. 1986 Oct;9(8):731-7. doi: 10.1002/mus.880090809.

DOI:10.1002/mus.880090809
PMID:3785284
Abstract

An ischemic forearm test with simultaneous measurement of both lactate and ammonia can be used as a screening method for myoadenylate deaminase deficiency (MADD) and for various glyco(geno)lytic defects. A standardized and a nonstandardized test have been compared in a group of 186 patients with exertional myalgia. Standardization of the ischemic forearm test has led to greater yields of both lactate and ammonia in venous return blood of patients and controls. The sensitivity of the proposed test procedure in detecting MADD patients was 100%, whereas the specificity amounted to 98.8% among exertional myalgia patients.

摘要

一种同时测量乳酸和氨的缺血性前臂试验可作为筛查肌腺苷酸脱氨酶缺乏症(MADD)和各种糖(原)酵解缺陷的方法。在一组186例运动性肌痛患者中比较了标准化试验和非标准化试验。缺血性前臂试验的标准化使得患者和对照组静脉回流血中乳酸和氨的产量更高。所提出的检测程序在检测MADD患者方面的敏感性为100%,而在运动性肌痛患者中的特异性为98.8%。

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