Department of Orthopedics and Trauma Surgery, Lucerne Cantonal Hospital, Spitalstraβe 16, 6000, Lucerne, Switzerland.
AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos, Switzerland.
Sci Rep. 2023 Oct 18;13(1):17750. doi: 10.1038/s41598-023-43929-7.
Lateral wall thickness is a known predictor for postoperative stability of trochanteric femoral fractures and occurrence of secondary lateral wall fractures. Currently, the AO/OTA classification relies on the absolute lateral wall thickness (aLWT) to distinguish between stable A1.3 and unstable A2.1 fractures that does not take interpersonal patient differences into account. Thus, a more individualized and accurate measure would be favorable. Therefore, we proposed and validated a new patient-specific measure-the relative lateral wall thickness (rLWT)-to consider individualized measures and hypothesized its higher sensitivity and specificity compared with aLWT. First, in 146 pelvic radiographs of patients without a trochanteric femoral fracture, the symmetry of both caput-collum-diaphyseal angle (CCD) and total trochanteric thickness (TTT) was assessed to determine whether the contralateral side can be used for rLWT determination. Then, data of 202 patients were re-evaluated to compare rLWT versus previously published aLWT. Bilateral symmetry was found for both CCD and TTT (p ≥ 0.827), implying that bone morphology and geometry of the contralateral intact side could be used to calculate rLWT. Validation revealed increased accuracy of the rLWT compared with the gold standard aLWT, with increased specificity by 3.5% (Number Needed to Treat = 64 patients) and sensitivity by 1% (Number Needed to Treat = 75 patients). The novel rLWT is a more accurate and individualized predictor of secondary lateral wall fractures compared with the standard aLWT. This study established the threshold of 50.5% rLWT as a reference value for predicting fracture stability in trochanteric femoral fractures.
外侧壁厚度是预测转子间股骨骨折术后稳定性和发生继发性外侧壁骨折的已知指标。目前,AO/OTA 分类依赖于绝对外侧壁厚度 (aLWT) 来区分稳定的 A1.3 和不稳定的 A2.1 骨折,但没有考虑到个体患者的差异。因此,更个体化和准确的测量方法将是有利的。因此,我们提出并验证了一种新的患者特异性测量方法——相对外侧壁厚度 (rLWT),以考虑个体化测量,并假设其与 aLWT 相比具有更高的敏感性和特异性。首先,在 146 例无转子间股骨骨折的骨盆 X 线片患者中,评估了双侧头干角 (CCD) 和总转子厚度 (TTT) 的对称性,以确定是否可以使用对侧来确定 rLWT。然后,重新评估了 202 例患者的数据,以比较 rLWT 与之前发表的 aLWT。CCD 和 TTT 双侧均存在对称性 (p≥0.827),这意味着对侧完整侧的骨骼形态和几何形状可用于计算 rLWT。验证结果表明,rLWT 的准确性高于金标准 aLWT,特异性提高了 3.5%(需要治疗的患者数=64 例),敏感性提高了 1%(需要治疗的患者数=75 例)。与标准的 aLWT 相比,新型 rLWT 是预测转子间股骨骨折继发性外侧壁骨折的更准确和个体化的指标。本研究建立了 50.5% rLWT 的阈值作为预测转子间股骨骨折稳定性的参考值。