Abeysekera Kushala W M, Srivastava Ankur, Rowe Ian, Jarvis Helen, Ryder Stephen D, Yeoman Andrew, Dillon John F, Rosenberg William
Department of Liver Medicine, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Population Health Sciences, University of Bristol Medical School, Bristol, UK.
Frontline Gastroenterol. 2023 Jun 15;14(6):483-490. doi: 10.1136/flgastro-2023-102415. eCollection 2023.
The increasing availability of non-invasive tests (NITs) has created the opportunity to explore their use in improving risk stratification of advanced liver disease. The study aimed to determine the attitudes and practices among UK secondary care specialists, focusing primarily on attitudes to fibrosis assessment and the use of NITs.
Two web-based surveys were circulated, first between 2014 and 2015 (survey 1), and again in 2021 (survey 2). The surveys were promoted via the British Society of Gastroenterology, the British Association for the Study of the Liver and using Twitter.
In survey 1, 215 healthcare professionals (HCPs) completed the online survey. 112 HCPs completed survey 2. 71 acute UK trusts were represented in survey 1 compared with 60 trusts in survey 2. Between the two surveys, the proportion of HCPs performing fibrosis assessment in all or nearly all cases rose from 45.1% to 74.1% (χ=25.01; p<0.0001). 46.5% (n=33/71) respondents in acute services reported the use of NITs in clinical pathways in survey 1, rising to 70.0% (n=42/60) in survey 2 (χ=7.35; p=0.007). Availability of tests has increased but is not universal. The proportion reporting availability as a barrier to uptake fell from 57.2% of responses in survey 1 to 38.4% in 2021 χ=11.01; p=0.0009).
Between 2014 and 2021, the role of NITs in fibrosis assessment has risen substantially, as has the proportion of clinicians using NITs in clinical pathways to assess risk of liver disease. Poor access to NITs remains the predominant barrier.
非侵入性检测(NITs)的可及性日益提高,为探索其在改善晚期肝病风险分层中的应用创造了机会。本研究旨在确定英国二级医疗专家的态度和实践,主要关注对纤维化评估的态度以及NITs的使用情况。
进行了两次基于网络的调查,第一次在2014年至2015年期间(调查1),第二次在2021年(调查2)。通过英国胃肠病学会、英国肝脏研究协会以及推特推广这些调查。
在调查1中,215名医疗保健专业人员(HCPs)完成了在线调查。112名HCPs完成了调查2。调查1中有71家急性英国信托机构参与,而调查2中有60家信托机构参与。在两次调查之间,在所有或几乎所有病例中进行纤维化评估的HCPs比例从45.1%上升至74.1%(χ=25.01;p<0.0001)。在调查1中,急性服务部门46.5%(n=33/71)的受访者报告在临床路径中使用了NITs,在调查2中这一比例升至70.0%(n=42/60)(χ=7.35;p=0.007)。检测的可及性有所提高,但并不普遍。将可及性报告为采用障碍的比例从调查1中回复的57.2%降至2021年的38.4%(χ=11.01;p=0.0009)。
在2014年至2021年期间,NITs在纤维化评估中的作用大幅上升,临床医生在临床路径中使用NITs评估肝病风险的比例也有所上升。NITs获取不便仍然是主要障碍。