Institute of Pharmaceutical Research, GLA University, Mathura, 281406, UP, India.
Med Chem. 2024;20(2):115-129. doi: 10.2174/0115734064274748231005074100.
Chromenes are a significant family of heterocyclic chemicals that have a wide range of biological applications, a simple chemical structure, and only mildly undesirable side effects. The synthesis of a wide range of chromene analogs that displayed unexpected behaviors via numerous mechanisms was investigated by a number of different research teams, which led to the discovery of multiple pathways for their synthesis. In addition, different chromene-fused heterocycles exhibit a wide variety of fascinating biological actions, including those that are anticancer, anticonvulsant, antibacterial, anticholinesterase, antituberculosis, and anti-diabetic. In light of this, the purpose of this study is to highlight the many synthesis techniques and antibacterial activity associated with chromene-fused heterocyclic compounds. Moreover, such research can open avenues for exploring other therapeutic applications of these compounds in various disease areas, as their biological activities extend beyond antibacterial effects.
色烯是一类具有广泛生物学应用的重要杂环化合物，它们具有简单的化学结构和温和的不良反应。许多不同的研究小组研究了合成具有多种机制的广泛色烯类似物，这导致了它们合成的多种途径的发现。此外，不同的色烯稠合杂环化合物表现出广泛的迷人的生物学作用，包括抗癌、抗惊厥、抗菌、抗胆碱酯酶、抗结核和抗糖尿病。有鉴于此，本研究的目的是强调与色烯稠合杂环化合物相关的许多合成技术和抗菌活性。此外，此类研究可以为探索这些化合物在各种疾病领域的其他治疗应用开辟途径，因为它们的生物学活性不仅限于抗菌作用。
