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胎儿皮质移植可改善新生儿额叶皮质损伤同侧的丘脑萎缩。

Fetal cortical transplants ameliorate thalamic atrophy ipsilateral to neonatal frontal cortex lesions.

作者信息

Sharp F R, Gonzalez M F

出版信息

Neurosci Lett. 1986 Nov 11;71(2):247-51. doi: 10.1016/0304-3940(86)90567-7.

DOI:10.1016/0304-3940(86)90567-7
PMID:3785746
Abstract

Thalamic atrophy develops ipsilateral to neonatal frontal cortex lesions. Fetal cortex transplants placed in these lesions at birth ameliorate the thalamic atrophy. This could be due to trophic effects of the transplants on the neonatal host thalamus, host cortex, or both.

摘要

丘脑萎缩发生在新生儿额叶皮质损伤的同侧。出生时置于这些损伤部位的胎儿皮质移植可改善丘脑萎缩。这可能是由于移植对新生儿宿主丘脑、宿主皮质或两者的营养作用。

相似文献

1
Fetal cortical transplants ameliorate thalamic atrophy ipsilateral to neonatal frontal cortex lesions.胎儿皮质移植可改善新生儿额叶皮质损伤同侧的丘脑萎缩。
Neurosci Lett. 1986 Nov 11;71(2):247-51. doi: 10.1016/0304-3940(86)90567-7.
2
Fetal cortical transplants reduce the thalamic atrophy induced by frontal cortical lesions in newborn rats.胎儿皮质移植可减轻新生大鼠额叶皮质损伤所致的丘脑萎缩。
Neurosci Lett. 1989 Mar 13;98(1):33-8. doi: 10.1016/0304-3940(89)90369-8.
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Adult rat motor cortex connections to thalamus following neonatal and juvenile frontal cortical lesions: WGA-HRP and amino acid studies.新生和幼年额叶皮质损伤后成年大鼠运动皮质与丘脑的连接：WGA-HRP和氨基酸研究
Brain Res. 1986 Dec;395(2):169-87. doi: 10.1016/s0006-8993(86)80196-2.
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Specific invasion of occipital-to-frontal neocortical grafts by axons from the lateral posterior thalamic nucleus consecutive to neonatal lesion of the rat occipital cortex.大鼠枕叶皮质新生期损伤后，外侧后丘脑核轴突对枕叶至额叶新皮质移植组织的特异性侵入。
Exp Neurol. 1998 Jul;152(1):64-73. doi: 10.1006/exnr.1998.6830.
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Fetal cortical transplants reduce motor deficits resulting from neonatal damage to the rat's frontal cortex.胎儿皮质移植可减少新生大鼠额叶皮质损伤所致的运动功能缺陷。
Neurosci Lett. 1990 Feb 5;109(1-2):102-6. doi: 10.1016/0304-3940(90)90545-k.
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Homotopic, but not heterotopic, fetal cortical transplants can result in functional sparing following neonatal damage to the frontal cortex in rats.
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Fetal frontal cortex transplant (14C) 2-deoxyglucose uptake and histology: survival in cavities of host rat brain motor cortex.
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Temporal factors influence recovery of function after embryonic brain tissue transplants in adult rats with frontal cortex lesions.
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Neonatal frontal cortex grafts fail to attenuate behavioural deficits or abnormal cortical morphogenesis.
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Motor deficits are produced by removing some cortical transplants grafted into injured sensorimotor cortex of neonatal rats.通过移除移植到新生大鼠受伤感觉运动皮层的一些皮质移植物，可导致运动功能缺陷。
J Neural Transplant Plast. 1991;2(3-4):221-33. doi: 10.1155/NP.1991.221.

引用本文的文献

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Responses to electrical stimulation of the recipient's brain in rat somatosensory cortical neurons transplanted into the area of vibrissa representation in the neocortex.
Neurosci Behav Physiol. 1989 Nov-Dec;19(6):449-56. doi: 10.1007/BF01181857.
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Isochronic transplantation of neonatal grafts in the visual cortex of cats: responsiveness, ocular dominance and specificity of cortical cells to visual stimulation.猫视觉皮层新生儿移植物的等时移植：皮层细胞对视觉刺激的反应性、眼优势和特异性
Exp Brain Res. 1991;87(1):181-92. doi: 10.1007/BF00228519.