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利用非靶向代谢组学探索水生微生物群落的进展与挑战。

Progress and challenges in exploring aquatic microbial communities using non-targeted metabolomics.

机构信息

University of California San Diego, Scripps Institution of Oceanography, La Jolla, CA, USA.

J. Craig Venter Institute, Microbial and Environmental Genomics Group, La Jolla, CA, USA.

出版信息

ISME J. 2023 Dec;17(12):2147-2159. doi: 10.1038/s41396-023-01532-8. Epub 2023 Oct 19.

DOI:10.1038/s41396-023-01532-8
PMID:37857709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10689791/
Abstract

Advances in bioanalytical technologies are constantly expanding our insights into complex ecosystems. Here, we highlight strategies and applications that make use of non-targeted metabolomics methods in aquatic chemical ecology research and discuss opportunities and remaining challenges of mass spectrometry-based methods to broaden our understanding of environmental systems.

摘要

生物分析技术的进步不断拓展着我们对复杂生态系统的认识。在这里,我们重点介绍了在水生化学生态学研究中利用非靶向代谢组学方法的策略和应用,并讨论了基于质谱的方法拓宽我们对环境系统理解的机会和仍存在的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/353f/10689791/7c4f3717c759/41396_2023_1532_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/353f/10689791/4693fd98f82e/41396_2023_1532_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/353f/10689791/a835fd52ce78/41396_2023_1532_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/353f/10689791/7c4f3717c759/41396_2023_1532_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/353f/10689791/4693fd98f82e/41396_2023_1532_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/353f/10689791/a835fd52ce78/41396_2023_1532_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/353f/10689791/7c4f3717c759/41396_2023_1532_Fig3_HTML.jpg

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Nat Commun. 2023 Dec 20;14(1):8488. doi: 10.1038/s41467-023-44035-y.
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Growth-stage-related shifts in diatom endometabolome composition set the stage for bacterial heterotrophy.硅藻内膜代谢组组成中与生长阶段相关的变化为细菌异养奠定了基础。
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