Bruce D A, Schut L
Childs Brain. 1979;5(3):192-203. doi: 10.1159/000119818.
The clinical course of 42 children with lipomatous lesions of the lower spine is reviewed. Good neurological exam, IVP and myelography are considered essential components of the preoperative studies. The surgical aim is to free all intra- to extradural adhesions with dural grafting, if necessary. The results suggest that early corrective surgery within the first few weeks to months of life is the most satisfactory approach to preserving normal neurological and urological function in these children. 88% of children not operated on early developed progressive loss of neurological function and while delayed surgery frequently stopped progression of the disease it rarely returned the children to a normal state.
回顾了42例下脊柱脂肪瘤性病变患儿的临床病程。良好的神经系统检查、静脉肾盂造影（IVP）和脊髓造影被认为是术前研究的重要组成部分。手术目的是在必要时通过硬脊膜移植解除所有硬膜内至硬膜外粘连。结果表明，在出生后的头几周至数月内尽早进行矫正手术是在这些患儿中保留正常神经和泌尿功能的最令人满意的方法。88%未早期手术的患儿出现神经功能进行性丧失，虽然延迟手术常常能阻止疾病进展，但很少能使患儿恢复到正常状态。
