Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu, China.
BMC Ophthalmol. 2023 Oct 19;23(1):418. doi: 10.1186/s12886-023-03109-7.
Xen Gel Stent implant is a new minimally invasive surgical treatment for glaucoma that has been proven effectiveness and safety profile. However, it may also lead to some complications. Xen Gel Stent occlusion is a relatively rare complication reported less frequently and has limited treatment experience. In our case report, we proposed a novel surgical treatment using a 10 - 0 nylon suture to successfully recanalize the occluded Xen45 Gel Stent.
A 16-year-old female patient had bilateral juvenile glaucoma for the past 5 years. Her right eye had undergone three glaucoma surgeries but failed. At a presentation to our hospital, the right eye's intraocular pressure (IOP) was 30 mmHg despite applying four different active principles. Xen45 Gel Stent implant was chosen for treatment, but six days after implantation, the IOP rose to 40 mmHg as a result of an anterior chamber tip occlusion of the Xen45 Gel Stent. Nd: YAG laser shockwave therapy was attempted but failed. The patient eventually had to return to the operating room for a revision procedure. The Xen45 Gel Stent was recanalized from the ab externo by making an L-shaped conjunctival incision at the fornix base and threading a 10 - 0 nylon suture through it. The IOP was successfully controlled in the 11-month follow-up without medication.
If postoperative occlusion arises after Xen45 Gel Stent implantation, surgery using 10 - 0 nylon suture to recanalize Xen45 Gel Stent should be considered as a relatively safe, effective that does not require removal of Xen45 Gel Stent.
Xen Gel 支架植入术是一种新的治疗青光眼的微创手术,已被证明具有有效性和安全性。然而,它也可能导致一些并发症。Xen Gel 支架阻塞是一种相对罕见的并发症,报道较少,治疗经验有限。在我们的病例报告中,我们提出了一种使用 10-0 尼龙缝线的新的手术治疗方法,成功地使阻塞的 Xen45 Gel 支架再通。
一名 16 岁女性患者过去 5 年来患有双侧青少年青光眼。她的右眼已经接受了三次青光眼手术,但都失败了。在我院就诊时,右眼的眼压(IOP)为 30mmHg,尽管使用了四种不同的活性药物。选择 Xen45 Gel 支架植入进行治疗,但植入后 6 天,由于 Xen45 Gel 支架前房尖端阻塞,IOP 升高至 40mmHg。尝试了 Nd:YAG 激光冲击波治疗,但失败了。患者最终不得不返回手术室进行修正手术。通过在穹隆基底处做一个 L 形结膜切口,并将一根 10-0 尼龙缝线穿过切口,从外至内重新疏通 Xen45 Gel 支架。在 11 个月的随访中,眼压得到成功控制,无需药物治疗。
如果 Xen45 Gel 支架植入术后出现阻塞,应考虑使用 10-0 尼龙缝线重新疏通 Xen45 Gel 支架,这是一种相对安全、有效的方法,不需要取出 Xen45 Gel 支架。