[Evaluation of the effectiveness of ALG in clinical kidney transplantation in alternating studies].

The efficacy of ALG (horse serum against cultured human lymphocytes) in addition to a standard azathioprine and steroid regimen has been investigated in an alternating series of 70 renal transplantations in adults. Patient survival was almost identical in both groups. Transplant survival after 2 years was 64% in the ALG group as opposed to 48% in the group without ALG. In agreement with current literature, immunosuppression with ALG in high dosage seems to be justified.