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Delayed post-operative aggravation of sleep related disturbances in patients of basilar invagination with Chiari malformation: case report and review of the literature.颅底凹陷伴 Chiari 畸形患者术后睡眠相关障碍延迟加重:病例报告及文献复习。
Br J Neurosurg. 2023 Dec;37(6):1867-1871. doi: 10.1080/02688697.2021.1947981. Epub 2021 Jul 10.
3
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Chiari畸形患者后颅窝减压术后的呼吸骤停:综述

Respiratory arrest after posterior fossa decompression in patients with Chiari malformations: An overview.

作者信息

Atallah Oday, Wireko Andrew Awuah, Chaurasia Bipin

机构信息

Department of Neurosurgery, Hannover Medical School, Hannover, Germany.

Department of Neurosurgery, Sumy State University, Sumy, Ukraine.

出版信息

J Craniovertebr Junction Spine. 2023 Jul-Sep;14(3):217-220. doi: 10.4103/jcvjs.jcvjs_70_23. Epub 2023 Sep 18.

DOI:10.4103/jcvjs.jcvjs_70_23
PMID:37860018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10583799/
Abstract

BACKGROUND

Chiari malformation type 1 (CM1) is a structural abnormality in the skull and cerebellum, causing cerebellar tonsils to shift downward. Decompression of the posterior fossa is a common surgical method to relieve symptoms and prevent neurological deterioration. After posterior fossa decompression (PFD), individuals with CM1 were more likely to have respiratory arrest. Here, we present, for the first time, a comprehensive overview of the potential risk factors and causes of respiratory arrest following PFD.

METHODS

A review of the literature highlighting the risk factors for postoperative respiratory arrest in CM1 patients was conducted in the databases of PubMed, Medline, and Google Scholar.

RESULTS

Patients with syringomyelia and CM1 are at increased risk for respiratory arrest due to a number of factors, including impaired respiratory mechanics, central respiratory center dysfunction from edema or ischemia, intraoperative brain stem ischemia, and delayed gastric emptying from autonomic dysfunction. Occipitalization of the first cervical vertebra, basilar impression, and fusion of C2-C3 are all risk factors for respiratory arrest.

CONCLUSION

Implications for CM1 patient care and prospects for further investigation of postoperative respiratory arrest's causes and risk factors were discussed.

摘要

背景

1型Chiari畸形(CM1)是一种颅骨和小脑的结构异常,导致小脑扁桃体向下移位。后颅窝减压术是缓解症状和预防神经功能恶化的常见手术方法。后颅窝减压术(PFD)后,CM1患者更易发生呼吸骤停。在此,我们首次全面概述了PFD后呼吸骤停的潜在危险因素和原因。

方法

在PubMed、Medline和谷歌学术数据库中对强调CM1患者术后呼吸骤停危险因素的文献进行综述。

结果

由于多种因素,包括呼吸力学受损、水肿或缺血导致的中枢呼吸中心功能障碍、术中脑干缺血以及自主神经功能障碍导致的胃排空延迟,患有脊髓空洞症和CM1的患者呼吸骤停风险增加。第一颈椎枕化、基底凹陷和C2-C3融合都是呼吸骤停的危险因素。

结论

讨论了对CM1患者护理的意义以及对术后呼吸骤停原因和危险因素进一步研究的前景。