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急性感染相关脾梗死:病例报告及文献复习。

Acute infection associated with splenic infarction: a case report and review of the literature.

机构信息

Center of Infectious Disease and Pathogen Biology, Department of Infectious Diseases, The First Hospital of Jilin University, Changchun, China.

出版信息

Front Cell Infect Microbiol. 2023 Oct 4;13:1234447. doi: 10.3389/fcimb.2023.1234447. eCollection 2023.

Abstract

infection often involves multiple organ systems with non-specific clinical manifestations, and cutaneous involvement is uncommon. Splenic infarction and leukocytoclastic vasculitis also rarely occur together in the course of brucellosis infection. We report the case of a 47-year-old man with combined with splenic infarction. The patient presented with fever; large liver, spleen, and lymph nodes; muscle and joint pain; positive laboratory tests for blood cultures (); and imaging suggestive of splenic infarction. After treatment with streptomycin, doxycycline, and rifampicin, the patient's clinical symptoms and splenic damage improved. Detailed history taking, correct interpretation of laboratory results, and knowledge of rare complications of human brucellosis facilitate early diagnosis and treatment of the disease.

摘要

感染常涉及多个器官系统,临床表现非特异性,皮肤受累并不常见。在布鲁氏菌感染过程中,脾梗死和白细胞碎裂性血管炎也很少同时发生。我们报告了一例 47 岁男性患者,其同时患有脾梗死。患者表现为发热;肝、脾和淋巴结肿大;肌肉和关节疼痛;血培养实验室检查阳性();影像学提示脾梗死。患者接受链霉素、多西环素和利福平治疗后,临床症状和脾损伤均得到改善。详细的病史询问、正确解读实验室结果以及了解人类布鲁氏菌病罕见的并发症有助于早期诊断和治疗该疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/269a/10582943/b2d017dce776/fcimb-13-1234447-g001.jpg

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