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[脑肿瘤患者抑郁综合征的合理治疗]

[Rational treatment of depressive syndromes in brain tumor patients].

作者信息

Knabbe Johannes, Kowalski Thomas, Seliger Corinna

机构信息

Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.

Klinik für Neurologie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Bochum, Deutschland.

出版信息

Nervenarzt. 2024 Feb;95(2):125-132. doi: 10.1007/s00115-023-01558-5. Epub 2023 Oct 20.

Abstract

BACKGROUND

Brain tumors represent a disease that causes both physical and psychological distress for those affected. The pharmacological treatment of depressive symptoms in particular has not been sufficiently researched in these patients. Depression can severely affect the quality of life and has an impact on the course of the disease.

OBJECTIVE

The aim of this work is to describe the diagnosis and treatment of depressive symptoms in brain tumor patients.

MATERIAL AND METHODS

For this work a comprehensive literature search was conducted to identify relevant studies addressing the topic of depressive symptoms in brain tumors. The included studies were critically appraised to ensure their quality and relevance.

RESULTS

The review of the literature revealed that depressive symptoms are a common complication in brain tumor patients. It was found that there are no studies to date on the efficacy of antidepressant medications in brain tumor patients.

DISCUSSION

The results of this work highlight the need to pay increased attention to mental health in brain tumor patients. It is important that healthcare professionals identify depression in these patients at an early stage and provide appropriate interventions to improve their quality of life. Future research should focus on further exploring the mechanisms behind the association between brain tumors and depression in order to develop targeted and effective intervention options.

摘要

背景

脑肿瘤是一种给患者带来身体和心理痛苦的疾病。尤其是这些患者抑郁症状的药物治疗尚未得到充分研究。抑郁症会严重影响生活质量,并对疾病进程产生影响。

目的

这项工作的目的是描述脑肿瘤患者抑郁症状的诊断和治疗。

材料与方法

为此项工作进行了全面的文献检索,以确定涉及脑肿瘤患者抑郁症状主题的相关研究。对纳入的研究进行严格评估,以确保其质量和相关性。

结果

文献综述显示,抑郁症状是脑肿瘤患者的常见并发症。结果发现,迄今为止尚无关于抗抑郁药物对脑肿瘤患者疗效的研究。

讨论

这项工作的结果凸显了需要更加关注脑肿瘤患者的心理健康。医疗保健专业人员尽早识别这些患者的抑郁症并提供适当干预措施以改善其生活质量非常重要。未来的研究应专注于进一步探索脑肿瘤与抑郁症之间关联背后的机制,以便开发有针对性的有效干预方案。

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