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眼部带状疱疹患者住院率上升——一项跨学科回顾性分析

Increasing hospitalisation of patients with herpes zoster ophthalmicus-an interdisciplinary retrospective analysis.

作者信息

Diehl Rebecca, Wiedenmann Cornelius, Reinhard Thomas, Böhringer Daniel, Schauer Franziska

机构信息

Department of Dermatology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2024 Feb;262(2):583-588. doi: 10.1007/s00417-023-06277-w. Epub 2023 Oct 20.

DOI:10.1007/s00417-023-06277-w
PMID:37861849
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10844404/
Abstract

BACKGROUND

The occurrence of herpes zoster is rising globally. Future trends will be influenced by changes in population demographics and the growing number of patients at risk. Overall this poses a challenge for healthcare systems.

METHODS

In our interdisciplinary, single-centre retrospective analysis, we aimed to assess the burden of the disease within the Department of Dermatology and the Eye Centre from the Medical Centre, University of Freiburg from 2009-2022. We obtained data from 3034 cases coded using the ICD-10 B02.x. Patients were characterised by sex, age, year of treatment, and type of treatment (inpatient vs. outpatient).

RESULTS

Overall we observed a 200% increase in the number of herpes zoster patients over the 13-year period. Upon closer analysis, this was mainly due to a rise in inpatient treatment for herpes zoster ophthalmicus.

CONCLUSIONS

If the incidence of herpes zoster ophthalmicus continues to increase at the current rate the number of hospitalisations of zoster ophthalmicus would double by 2040, assuming guideline-appropriate treatment. Overall, the results show a growing need for inpatient ophthalmological care.

摘要

背景

带状疱疹的发病率在全球范围内呈上升趋势。未来趋势将受到人口结构变化和高危患者数量增加的影响。总体而言,这给医疗系统带来了挑战。

方法

在我们的多学科单中心回顾性分析中,我们旨在评估2009年至2022年期间弗赖堡大学医学中心皮肤科和眼科中心内该疾病的负担。我们从使用ICD-10 B02.x编码的3034例病例中获取数据。患者的特征包括性别、年龄、治疗年份和治疗类型(住院治疗与门诊治疗)。

结果

总体而言,我们观察到在这13年期间带状疱疹患者数量增加了200%。经过仔细分析,这主要是由于眼部带状疱疹住院治疗的增加。

结论

如果眼部带状疱疹的发病率继续以目前的速度上升,假设采用符合指南的治疗方法,到2040年眼部带状疱疹的住院人数将翻倍。总体而言,结果表明对住院眼科护理的需求日益增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a64/10844404/f7d8d7517700/417_2023_6277_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a64/10844404/b68ade91dda3/417_2023_6277_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a64/10844404/f7d8d7517700/417_2023_6277_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a64/10844404/b68ade91dda3/417_2023_6277_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a64/10844404/f7d8d7517700/417_2023_6277_Fig2_HTML.jpg

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本文引用的文献

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Increase in inpatient cases of zoster in Germany: Possible causes and recommendations for prevention.德国带状疱疹住院病例增加:可能原因及预防建议
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Antioxidant and inflammatory biomarkers in herpes zoster.带状疱疹的抗氧化和炎症生物标志物。
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Arch Dermatol Res. 2022 Jul;314(5):427-437. doi: 10.1007/s00403-021-02244-9. Epub 2021 Jun 2.
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