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交叉疫情:津巴布韦艾滋病毒感染者在 COVID-19 疫情期间继续利用艾滋病毒护理和治疗服务的预测因素。

Intersecting Epidemics: The Predictors of Continued Utilization of HIV Care and Treatment Services During the COVID-19 Outbreak Among People Living with HIV in ZIMBABWE.

机构信息

Demography and Population Studies Programme, Schools of Public Health and Social Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Zimbabwe National Network of People Living With HIV (ZNNP+), Harare, Zimbabwe.

出版信息

AIDS Behav. 2024 Oct;28(Suppl 1):34-46. doi: 10.1007/s10461-023-04194-x. Epub 2023 Oct 20.

Abstract

Globally, there have been considerable achievements towards HIV care and treatment. AIDS-related deaths have been reduced by 60% since the peak in 2004. Potentially, the fight against the HIV epidemic was made more difficult with the outbreak of COVID-19. Thus, this study examined the implications of COVID-19 in the utilization of HIV care and treatment services among people living with HIV on antiretroviral therapy (ART) in Zimbabwe. The study aimed to identify the critical factors defining the utilization of HIV services at the advent of COVID-19 using the fifth revision of the Anderson Behavioral Model of Healthcare Utilization. The study utilized a concurrent triangulation design of which only one data collection phase was used. The quantitative data was collected from 2,157 people living with HIV on antiretroviral viral therapy through a structured interviewer-administered questionnaire. On the other hand, qualitative data was collected through in-depth interviews. Regarding accessing ART refills, the study findings revealed that adolescents aged 15-19 (aOR = 2.16; 95% CI: 1.18-3.96) had higher odds of utilizing ART refills compared to their counterparts who were aged 20-24. Living in a rural area was associated with higher odds of utilizing the ART refill service (aOR = 2.20; 95% CI: 1.49-3.24). Regarding accessing viral load monitoring adults aged 25-39 (aOR = 0.41; 95% CI: 0.26-0.66) were less likely to utilize viral load monitoring compared to young people aged 20-24. Being vaccinated for COVID-19 was significantly associated with higher odds of utilizing the viral load monitoring service (aOR = 1.97; 95% CI: 1.36-2.87) than those not yet vaccinated. Living in a rural area was associated with higher odds of utilizing viral load monitoring (aOR = 1.50; 95% CI: 1.09-2.08). Regarding tuberculosis preventative therapy, adults aged 25-39 (aOR = 0.30; 95% CI: 0.20-0.47) were less likely to utilize tuberculosis preventative therapy compared to young people aged 20-24. Being vaccinated for COVID-19 was significantly associated with higher odds of utilizing tuberculosis preventative therapy (aOR = 1.59; 95% CI: 1.12-2.25) than those not yet vaccinated. Living in a rural area was associated with higher odds of utilizing tuberculosis preventive therapy (aOR = 1.58; 95% CI: 1.19-2.08). Regarding tuberculosis screening being vaccinated for COVID-19 was significantly associated with higher odds of utilizing tuberculosis screening services (aOR = 1.89; 95% CI: 1.41-2.54) than those not yet vaccinated. Although the severity of the COVID-19 pandemic has dwindled, COVID-19 appears to come and go in waves, and a few countries are still recording relatively high cases. It is therefore likely that the factors associated with utilization of HIV services identified by the study such as age, residence, type of health facility, vaccination of COVID-19 and fear of contracting COVID-19, among others, need to be included when planning to improve access to health utilization.

摘要

在全球范围内,艾滋病的护理和治疗已经取得了相当大的成就。自 2004 年达到峰值以来,艾滋病相关死亡人数减少了 60%。然而,随着 COVID-19 的爆发,艾滋病的防控工作变得更加困难。因此,本研究考察了 COVID-19 对津巴布韦接受抗逆转录病毒治疗(ART)的艾滋病毒感染者利用艾滋病护理和治疗服务的影响。本研究旨在利用安德森医疗保健利用行为模型的第五版,确定在 COVID-19 出现时利用 HIV 服务的关键因素。该研究采用了同期三角设计,只使用了一个数据收集阶段。通过结构化访谈问卷,从 2157 名接受抗逆转录病毒治疗的艾滋病毒感染者中收集了定量数据。另一方面,通过深入访谈收集了定性数据。在获取 ART 续药方面,研究结果表明,与年龄在 20-24 岁的人相比,15-19 岁的青少年(aOR=2.16;95%CI:1.18-3.96)更有可能利用 ART 续药服务。居住在农村地区与利用 ART 续药服务的几率更高(aOR=2.20;95%CI:1.49-3.24)相关。在获取病毒载量监测方面,25-39 岁的成年人(aOR=0.41;95%CI:0.26-0.66)与 20-24 岁的年轻人相比,利用病毒载量监测的几率较低。接种 COVID-19 疫苗与利用病毒载量监测服务的几率更高(aOR=1.97;95%CI:1.36-2.87)有关,而未接种疫苗的人则较低。居住在农村地区与利用病毒载量监测的几率更高(aOR=1.50;95%CI:1.09-2.08)有关。在结核病预防性治疗方面,与 20-24 岁的年轻人相比,25-39 岁的成年人(aOR=0.30;95%CI:0.20-0.47)更不可能利用结核病预防性治疗。接种 COVID-19 疫苗与利用结核病预防性治疗的几率更高(aOR=1.59;95%CI:1.12-2.25)有关,而未接种疫苗的人则较低。居住在农村地区与利用结核病预防性治疗的几率更高(aOR=1.58;95%CI:1.19-2.08)有关。在结核病筛查方面,接种 COVID-19 疫苗与利用结核病筛查服务的几率更高(aOR=1.89;95%CI:1.41-2.54)有关,而未接种疫苗的人则较低。尽管 COVID-19 大流行的严重程度已经减弱,但 COVID-19 似乎呈波浪式出现和消失,一些国家仍在记录相对较高的病例。因此,在规划改善卫生服务的获取时,可能需要考虑研究中确定的与利用 HIV 服务相关的因素,如年龄、居住地、医疗机构类型、COVID-19 疫苗接种和对感染 COVID-19 的恐惧等。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f7a/11469966/02f463115a61/10461_2023_4194_Fig1_HTML.jpg

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