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Postacute sequelae of COVID-19 at 2 years.COVID-19 后 2 年的后遗症。
Nat Med. 2023 Sep;29(9):2347-2357. doi: 10.1038/s41591-023-02521-2. Epub 2023 Aug 21.
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Estimates of SARS-CoV-2 Seroprevalence and Incidence of Primary SARS-CoV-2 Infections Among Blood Donors, by COVID-19 Vaccination Status - United States, April 2021-September 2022.2021 年 4 月至 2022 年 9 月期间，按 COVID-19 疫苗接种状况划分的献血者中 SARS-CoV-2 血清流行率和原发性 SARS-CoV-2 感染发生率估计值-美国。
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Trajectory and Demographic Correlates of Antibodies to SARS-CoV-2 Nucleocapsid in Recently Infected Blood Donors, United States.近期感染的献血者中针对 SARS-CoV-2 核衣壳抗体的轨迹和人口统计学相关性，美国。
Emerg Infect Dis. 2023 Jul;29(7):1323-1329. doi: 10.3201/eid2907.230173. Epub 2023 May 10.
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Estimated SARS-CoV-2 antibody seroprevalence trends and relationship to reported case prevalence from a repeated, cross-sectional study in the 50 states and the District of Columbia, United States-October 25, 2020-February 26, 2022.2020年10月25日至2022年2月26日在美国50个州和哥伦比亚特区进行的一项重复横断面研究中，估计的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）抗体血清流行趋势及其与报告病例流行率的关系。
Lancet Reg Health Am. 2023 Feb;18:100403. doi: 10.1016/j.lana.2022.100403. Epub 2022 Dec 2.
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Longitudinal Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Antibody Responses and Identification of Vaccine Breakthrough Infections Among Healthcare Workers Using Nucleocapsid Immunoglobulin G.利用核衣壳 IgG 对医护人员进行的纵向严重急性呼吸综合征冠状病毒 2 疫苗抗体反应和疫苗突破性感染的鉴定。
J Infect Dis. 2022 Nov 28;226(11):1934-1942. doi: 10.1093/infdis/jiac420.
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Validation and performance of a multiplex serology assay to quantify antibody responses following SARS-CoV-2 infection or vaccination.一种用于量化SARS-CoV-2感染或疫苗接种后抗体反应的多重血清学检测方法的验证与性能评估
Clin Transl Immunology. 2022 Apr 26;11(4):e1385. doi: 10.1002/cti2.1385. eCollection 2022.
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Evaluation of the Performance of a Multiplexed Serological Assay in the Detection of SARS-CoV-2 Infections in a Predominantly Vaccinated Population.评价一种多重血清学检测方法在以疫苗接种人群为主的情况下对 SARS-CoV-2 感染的检测性能。
Microbiol Spectr. 2022 Feb 23;10(1):e0145421. doi: 10.1128/spectrum.01454-21.
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COVID-19 in patients with thoracic malignancies (TERAVOLT): first results of an international, registry-based, cohort study.胸恶性肿瘤患者的 COVID-19（TERAVOLT）：一项国际、基于登记的队列研究的初步结果。
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纵向核衣壳抗体检测揭示肺癌患者中有未记录的 SARS-CoV-2 感染。

Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer.

机构信息

Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Emory Vaccine Center, Emory University, Atlanta, GA, USA; Department of Microbiology and Immunology, Emory University, Atlanta, GA, USA.

出版信息

Cancer Cell. 2023 Nov 13;41(11):1838-1840. doi: 10.1016/j.ccell.2023.09.017. Epub 2023 Oct 19.

DOI:10.1016/j.ccell.2023.09.017
PMID:37863065
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11161204/
Abstract

Patients diagnosed with lung cancer (LC) exhibit increased susceptibility to SARS-CoV-2 infection. Rodilla et al. monitor the levels of plasma anti-nucleocapsid antibodies within a cohort of fully vaccinated LC patients and reveal that the actual infection rate is nearly twice the documented rate, indicating a significant prevalence of unreported cases.

摘要

诊断患有肺癌（LC）的患者对 SARS-CoV-2 感染的易感性增加。Rodilla 等人监测了一组完全接种疫苗的 LC 患者的血浆抗核衣壳抗体水平，结果显示实际感染率几乎是记录报告率的两倍，表明未报告的病例显著增多。