纵向核衣壳抗体检测揭示肺癌患者中有未记录的 SARS-CoV-2 感染。
Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer.
机构信息
Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Emory Vaccine Center, Emory University, Atlanta, GA, USA; Department of Microbiology and Immunology, Emory University, Atlanta, GA, USA.
出版信息
Cancer Cell. 2023 Nov 13;41(11):1838-1840. doi: 10.1016/j.ccell.2023.09.017. Epub 2023 Oct 19.
Abstract
Patients diagnosed with lung cancer (LC) exhibit increased susceptibility to SARS-CoV-2 infection. Rodilla et al. monitor the levels of plasma anti-nucleocapsid antibodies within a cohort of fully vaccinated LC patients and reveal that the actual infection rate is nearly twice the documented rate, indicating a significant prevalence of unreported cases.
摘要
诊断患有肺癌（LC）的患者对 SARS-CoV-2 感染的易感性增加。Rodilla 等人监测了一组完全接种疫苗的 LC 患者的血浆抗核衣壳抗体水平，结果显示实际感染率几乎是记录报告率的两倍，表明未报告的病例显著增多。
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