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与根间微型种植体植入相关的疼痛感知与预期:一项系统评价和荟萃分析。

Pain perception and expectation related to interradicular mini-implants insertion: a systematic review and meta-analysis.

作者信息

de Paiva Thais Teixeira, Barros Daniella Mascarenhas Calixto, Bittencourt Rafael Cunha, Savelli Marcella Baitelli Bruno, Lorenzoni Diego Coelho, de Alcantara Cury-Saramago Adriana, Mattos Claudia Trindade

机构信息

Department of Orthodontics, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil.

Faculdade de Odontologia, Disciplina de Ortodontia, Rua Mário Santos Braga, 30, 2° andar, sala 214, Centro, Niterói, CEP 24020-140, Brazil.

出版信息

Clin Oral Investig. 2023 Dec;27(12):7029-7043. doi: 10.1007/s00784-023-05311-9. Epub 2023 Oct 21.

DOI:10.1007/s00784-023-05311-9
PMID:37864604
Abstract

OBJECTIVES

The aim of this systematic review was to compare the expectation and perception of pain reported by patients before and after the installation of interradicular mini-implants.

MATERIALS AND METHODS

Electronic search was performed in six databases. Inclusion criteria were randomized controlled trials (RCTs) or non-randomized controlled clinical trials (nRCTs); studies using mini-implants in the interradicular region; assessment of pain intensity by visual analogue or numerical scale. The risk of bias assessment was based on the Rob 2 tool and Robins-I.

RESULTS

A total of 1566 articles were retrieved, and 21 met the eligibility criteria. Six were classified as high risk, one as critical and the other one as uncertain, according to the Robins-I tool. In articles evaluated by the Rob2 tool, ten were classified as serious risk and three as moderate risk. A meta-analysis was also performed. Weighted means were calculated among the studies using the random-effects model and forest plots were generated. Heterogeneity was assessed through the Q test and I statistics. It was observed, with moderate evidence, that on a scale of 0 to 10, the pain expectation (effect size 4.75) is higher than that effectively pain generated by the procedure (effect size 1.94).

CONCLUSION

Pain expectation was greater than that actually generated by the procedure, being almost non-existent 7 days postoperatively.

CLINICAL RELEVANCE

This study may help the clinician to reassure the patient regarding the sensations that could be experienced during and after the installation.

摘要

目的

本系统评价的目的是比较患者在植入根间微型种植体前后报告的疼痛预期和感知。

材料与方法

在六个数据库中进行电子检索。纳入标准为随机对照试验(RCT)或非随机对照临床试验(nRCT);在根间区域使用微型种植体的研究;通过视觉模拟或数字量表评估疼痛强度。偏倚风险评估基于Rob 2工具和Robins-I。

结果

共检索到1566篇文章,21篇符合纳入标准。根据Robins-I工具,6篇被归类为高风险,1篇为临界风险,另1篇为不确定风险。在使用Rob2工具评估的文章中,10篇被归类为严重风险,3篇为中度风险。还进行了荟萃分析。使用随机效应模型计算各研究的加权均值,并生成森林图。通过Q检验和I统计量评估异质性。有中等证据表明,在0至10分的量表上,疼痛预期(效应量4.75)高于该手术实际产生的疼痛(效应量1.94)。

结论

疼痛预期大于手术实际产生的疼痛,术后7天疼痛几乎不存在。

临床意义

本研究可能有助于临床医生就植入过程中和植入后可能经历的感觉向患者作出保证。

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本文引用的文献

1
Evaluation of the Patient-Reported Outcome Measures (PROMs) With Temporary Skeletal Anchorage Devices in Fixed Orthodontic Treatment: A Systematic Review.固定正畸治疗中使用临时骨锚定装置的患者报告结局指标(PROMs)评估:一项系统评价
Cureus. 2023 Mar 15;15(3):e36165. doi: 10.7759/cureus.36165. eCollection 2023 Mar.
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Comparison between Topical and Injection Anesthetics on Pain Related to Orthodontic Miniscrew Placement: A Split-mouth Study.局部麻醉和注射麻醉在正畸微螺钉植入相关疼痛中的比较:一项分口研究。
J Contemp Dent Pract. 2021 Jun 1;22(6):637-643.
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Assessment of Insertion Torque of Mini-implant and Its Correlation with Primary Stability and Pain Levels in Orthodontic Patients.
微型种植体植入扭矩评估及其与正畸患者初期稳定性和疼痛水平的相关性。
J Contemp Dent Pract. 2021 Jan 1;22(1):84-88.
4
Efficacy of compound topical anesthesia combined with photobiomodulation therapy in pain control for placement of orthodontic miniscrew: a double-blind, randomized clinical trial.复方局部麻醉联合光生物调节疗法在控制正畸微螺钉植入疼痛中的疗效:一项双盲、随机临床试验。
Lasers Med Sci. 2022 Feb;37(1):589-594. doi: 10.1007/s10103-021-03307-z. Epub 2021 Apr 2.
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Temporary deterioration of oral health-related quality of life (OHRQoL) in nonextraction and extraction modalities of comprehensive orthodontic treatment in adolescents.青少年综合正畸治疗中不拔牙和拔牙模式下口腔健康相关生活质量(OHRQoL)的暂时恶化。
Angle Orthod. 2020 Jul 1;90(4):578-586. doi: 10.2319/092319-607.1.
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A Clinical Trial of Photobiomodulation Effect on Orthodontic Microscrews Stability Using a 635 nm Red Laser Light.一种使用 635nm 红色激光的光生物调节对正畸微螺钉稳定性影响的临床试验。
Photobiomodul Photomed Laser Surg. 2020 Oct;38(10):607-613. doi: 10.1089/photob.2020.4863.
7
Oral health-related quality of life and clinical outcomes of immediately or delayed loaded implants in the rehabilitation of edentulous jaws: a retrospective comparative study.无牙颌修复中即刻或延期负载种植体的口腔健康相关生活质量及临床疗效:一项回顾性比较研究
Minerva Stomatol. 2018 Oct;67(5):189-195. doi: 10.23736/S0026-4970.18.04134-1. Epub 2018 Apr 16.
8
Impact of orthodontic treatment on adolescents' quality of life: a longitudinal evaluation of treated and untreated individuals.正畸治疗对青少年生活质量的影响:对治疗和未治疗个体的纵向评估。
Qual Life Res. 2018 Aug;27(8):2019-2026. doi: 10.1007/s11136-018-1830-7. Epub 2018 Mar 12.
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ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.ROBINS-I:一种评估干预性非随机研究偏倚风险的工具。
BMJ. 2016 Oct 12;355:i4919. doi: 10.1136/bmj.i4919.
10
Pain and discomfort following insertion of miniscrews and premolar extractions: A randomized controlled trial.微型螺钉植入和前磨牙拔除后的疼痛与不适:一项随机对照试验。
Angle Orthod. 2016 Nov;86(6):891-899. doi: 10.2319/123115-899.1. Epub 2016 Mar 29.