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Regulatory approval of islet transplantation for treatment of type 1 diabetes: Implications and what is on the horizon.

作者信息

Stabler Cherie L, Russ Holger A

机构信息

J. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL 32611, USA; Diabetes Institute, University of Florida, Gainesville, FL 32610, USA.

Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL 32610, USA; Diabetes Institute, University of Florida, Gainesville, FL 32610, USA.

出版信息

Mol Ther. 2023 Nov 1;31(11):3107-3108. doi: 10.1016/j.ymthe.2023.10.011. Epub 2023 Oct 20.

DOI:10.1016/j.ymthe.2023.10.011
PMID:37865099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10638039/
Abstract
摘要

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Regulatory approval of islet transplantation for treatment of type 1 diabetes: Implications and what is on the horizon.胰岛移植治疗1型糖尿病的监管批准:影响及未来展望。
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Considerations and challenges of islet transplantation and future therapies on the horizon.胰岛移植的考量与挑战以及即将出现的未来疗法。
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[Transplantation of the islets of Langerhans in patients with diabetes mellitus type 1].1型糖尿病患者胰岛移植
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Update on islet-cell transplantation for type 1 diabetes.1型糖尿病胰岛细胞移植的最新进展
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Hydrogel materials for the application of islet transplantation.水凝胶材料在胰岛移植中的应用。
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Using Mesenchymal Stromal Cells in Islet Transplantation.应用间充质基质细胞进行胰岛移植。
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Insulin independence by supplemental islet transplantation 5 years after initial islet transplantation.初次胰岛移植5年后通过补充胰岛移植实现胰岛素非依赖。
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Could islet transplantation be a potential cure for diabetes?胰岛移植能否成为糖尿病的一种潜在治愈方法?
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FDA regulation of allogeneic islets as a biological product.美国食品药品监督管理局对作为生物制品的同种异体胰岛的监管。
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Single-cell genomics and spatial transcriptomics in islet transplantation for diabetes treatment: advancing towards personalized therapies.用于糖尿病治疗的胰岛移植中的单细胞基因组学和空间转录组学:迈向个性化疗法
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Current status of pancreatic islet xenotransplantation.胰岛异种移植的现状
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Islet Cell Replacement and Regeneration for Type 1 Diabetes: Current Developments and Future Prospects.1型糖尿病的胰岛细胞替代与再生:当前进展与未来展望
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Clinical Islet Xenotransplantation: Development of Isolation Protocol, Anti-Rejection Strategies, and Clinical Outcomes.临床胰岛异种移植:分离方案的开发、抗排斥策略和临床结果。
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本文引用的文献

1
Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes.干细胞衍生胰岛替代治疗 1 型糖尿病的研究进展。
Cell Stem Cell. 2023 May 4;30(5):530-548. doi: 10.1016/j.stem.2023.04.002.
2
Long-term Outcomes With Islet-Alone and Islet-After-Kidney Transplantation for Type 1 Diabetes in the Clinical Islet Transplantation Consortium: The CIT-08 Study.临床胰岛移植联盟中1型糖尿病单独胰岛移植和肾后胰岛移植的长期结果:CIT-08研究
Diabetes Care. 2022 Oct 17;45(12):2967-75. doi: 10.2337/dc21-2688.
3
A Worldwide Survey of Activities and Practices in Clinical Islet of Langerhans Transplantation.一项关于临床胰岛移植活动与实践的全球调查。
Transpl Int. 2022 Aug 11;35:10507. doi: 10.3389/ti.2022.10507. eCollection 2022.
4
Islet cell transplantation hits a milestone.胰岛细胞移植取得了一个里程碑式的成果。
Am J Transplant. 2021 Aug;21(8):2625-2626. doi: 10.1111/ajt.16039.
5
Strategies for durable β cell replacement in type 1 diabetes.1 型糖尿病中β细胞持久替代的策略。
Science. 2021 Jul 30;373(6554):516-522. doi: 10.1126/science.abh1657.
6
Regulatory updates are needed to prevent the commercialization of islet transplantation in the United States.需要进行监管更新,以防止胰岛移植在美国商业化。
Am J Transplant. 2021 Jul;21(7):2620-2622. doi: 10.1111/ajt.16555. Epub 2021 Mar 20.
7
The demise of islet allotransplantation in the United States: A call for an urgent regulatory update.美国胰岛同种异体移植的衰落:呼吁紧急更新监管规定。
Am J Transplant. 2021 Apr;21(4):1365-1375. doi: 10.1111/ajt.16397. Epub 2021 Feb 10.
8
Solving the Puzzle of Immune Tolerance for β-Cell Replacement Therapy for Type 1 Diabetes.解决 1 型糖尿病β细胞替代治疗中免疫耐受问题。
Cell Stem Cell. 2020 Oct 1;27(4):505-507. doi: 10.1016/j.stem.2020.09.008.
9
Engineering immunomodulatory biomaterials for type 1 diabetes.用于1型糖尿病的工程免疫调节生物材料
Nat Rev Mater. 2019 Jun;4(6):429-450. doi: 10.1038/s41578-019-0112-5. Epub 2019 May 17.
10
Regulatory Framework for Advanced Therapy Medicinal Products in Europe and United States.欧美先进治疗药品监管框架
Front Pharmacol. 2019 Aug 30;10:921. doi: 10.3389/fphar.2019.00921. eCollection 2019.