• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[健康受试者单次服用精神药物的定量脑电图分析]

[Quantitative EEG analysis of a single dose of psychotropic drugs in healthy probands].

作者信息

Fischer W, Streubel F R, Heydenreich F, Rabending G

出版信息

Psychiatr Neurol Med Psychol (Leipz). 1986 Aug;38(8):450-5.

PMID:3786575
Abstract

In a series of 74 experiments in a double blind study, 25 healthy test persons were medicated with a single dose of Clomipramin, Desipramin, Imipramin, Diazepam, Carbamazepin, Haloperidol, and a placebo. At the end of one hour, and again at the end of three hours, an EEG was made whose frequency analysis revealed significant changes in about half the test persons. The antidepressives induced an increase in the theta waves, the slow alpha waves, and the slow beta waves, and a decrease in the fast alpha waves. The factors influencing the EEG are discussed.

摘要

在一项双盲研究的74次实验中,25名健康受试者分别单次服用氯米帕明、地昔帕明、丙咪嗪、地西泮、卡马西平、氟哌啶醇和安慰剂。在1小时结束时以及再次在3小时结束时,进行了脑电图检查,其频率分析显示约一半的受试者有显著变化。抗抑郁药导致θ波、慢α波和慢β波增加,快α波减少。讨论了影响脑电图的因素。

相似文献

1
[Quantitative EEG analysis of a single dose of psychotropic drugs in healthy probands].[健康受试者单次服用精神药物的定量脑电图分析]
Psychiatr Neurol Med Psychol (Leipz). 1986 Aug;38(8):450-5.
2
The influence of psychotropic drugs on the animal EEG: electrophysiological analysis of the effects of psychotropic drugs.精神药物对动物脑电图的影响:精神药物作用的电生理分析。
Electroencephalogr Clin Neurophysiol Suppl. 1982;36:566-76.
3
[The use of electrophysiological techniques to project typical psychotropic drug effects: some examples (author's transl)].[运用电生理技术预测典型精神药物效应:一些实例(作者译)]
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1981 Mar;12(1):21-32.
4
[Measuring reaction times in healthy probands before and following a single dose of psychotropic drugs].[测量健康受试者在单次服用精神药物前后的反应时间]
Psychiatr Neurol Med Psychol (Leipz). 1986 Oct;38(10):616-8.
5
[A computer-assisted EEG study on psychotropic properties of antiparkinsonian drugs].[抗帕金森病药物精神特性的计算机辅助脑电图研究]
Seishin Shinkeigaku Zasshi. 1992;94(3):238-62.
6
[Classification and determination of the pharmacodynamics of a new tetracyclic antidepressive agent, pirlindol, using pharmaco-EEG and psychometry].[运用药物脑电图和心理测量法对新型四环类抗抑郁药匹吲哚的药效学进行分类与测定]
Wien Klin Wochenschr. 1983 Jul 8;95(14):481-93.
7
[A quantitative pharmaco-EEG study on psychotropic properties of cerebral metabolic enhancers: comparison between young and elderly healthy volunteers].[脑代谢增强剂精神药理学特性的定量药物脑电图研究:年轻与老年健康志愿者的比较]
Seishin Shinkeigaku Zasshi. 1993;95(5):392-416.
8
Quantitative pharmaco-electroencephalographic differentiation between the CNS effects of bromocriptine and imipramine, drugs with qualitatively different antidepressant properties.溴隐亭和丙咪嗪对中枢神经系统作用的定量药物脑电图差异,这两种药物具有性质不同的抗抑郁特性。
Pharmacopsychiatry. 1987 Mar;20(2):54-9. doi: 10.1055/s-2007-1017075.
9
[Electrophysiological aspects in the mechanism of action of some psychotropic drug agents].
Eksp Med Morfol. 1976;15(1):46-52.
10
Encephalotropic and psychotropic effects of intravenous buflomedil in the elderly: double-blind, placebo-controlled pharmaco-EEG and psychometric studies.老年人静脉注射丁咯地尔的脑趋向性和精神趋向性效应:双盲、安慰剂对照的药物脑电图及心理测量学研究
Int J Clin Pharmacol Res. 1984;4(2):95-107.

引用本文的文献

1
Relationship between electrocortical activity and beta-adrenergic receptor function in the rat after chronic desimipramine treatment.慢性地昔帕明治疗后大鼠的皮层电活动与β-肾上腺素能受体功能之间的关系
J Neural Transm Gen Sect. 1989;78(1):73-87. doi: 10.1007/BF01247115.