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[测量健康受试者在单次服用精神药物前后的反应时间]

[Measuring reaction times in healthy probands before and following a single dose of psychotropic drugs].

作者信息

Fischer W, Streubel F R, Herzer H, Rabending G

出版信息

Psychiatr Neurol Med Psychol (Leipz). 1986 Oct;38(10):616-8.

PMID:3809304
Abstract

A single dose of Clomipramin, 50 mg; Amitriptylin, 50 mg; Desipramin, 50 mg; Imipramin, 50 mg; Diazepam, 10 mg; Carbamazepin, 200 mg; Haloperidol, 3 mg; were each administered orally, and Clomipramin, 25 mg was administered intravenously, and reaction times were measured and compared with those obtained after administering a placebo. The statistical examination was conducted using Wilcoxon's test. In the case of Amitriptylin, Diazepam, and Haloperidol, there was a statistically significant reduction in the reaction times.

摘要

分别口服单剂量氯米帕明50毫克、阿米替林50毫克、地昔帕明50毫克、丙咪嗪50毫克、地西泮10毫克、卡马西平200毫克、氟哌啶醇3毫克,静脉注射氯米帕明25毫克,测量反应时间并与服用安慰剂后的反应时间进行比较。采用威尔科克森检验进行统计学检验。在阿米替林、地西泮和氟哌啶醇的情况下,反应时间有统计学意义的缩短。

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