Pan Congcong, Pan Haiyan, Liang Dongmei, Liu Yuanyuan, Yin Sichun, Zhong Jianbo, He Songmei
School of Public Health, Guangdong Medical University, Dongguan, China.
Department of Infectious Diseases, Dongguan People's Hospital, Dongguan, China.
Front Glob Womens Health. 2023 Oct 6;4:1106959. doi: 10.3389/fgwh.2023.1106959. eCollection 2023.
The migrant population, consisting of individuals who relocate from rural to urban areas, faces unique challenges that heighten their vulnerability to HIV infection. These challenges stem from a combination of sociodemographic factors and limited access to healthcare services. Understanding the dynamics of HIV transmission within this population is crucial for the development of effective prevention strategies.
To investigate the factors contributing to HIV vulnerability among migrants, we conducted a cross-sectional study at Dongguan People's Hospital from January 1, 2018, to December 31, 2021. Our study focused on pregnant women living with HIV and their infants, with a particular emphasis on sociodemographic characteristics, HIV testing and treatment profiles, and neonatal clinical data. Data were systematically collected using standardized forms.
Analysis of data from 98 participants revealed noteworthy findings. No significant associations were observed between age, marital status, and educational background regarding HIV vulnerability. Similarly, factors such as the status of sexual partners, spousal therapy, and the number of children had no significant impact. However, our analysis highlighted the critical role of treatment strategies for HIV-positive women and the timing of antiretroviral therapy initiation for women with HIV, both of which were associated with HIV transmission ( < 0.05). Additionally, factors such as feeding type, neonatal antiretroviral prophylaxis, and preventive treatment strategies showed significant associations, while the preventive treatment program for neonates demonstrated no significant impact.
These findings provide valuable insights into the specific risk factors and barriers to HIV prevention faced by the migrant population in Dongguan. They underscore the importance of targeted interventions and policies aimed at curtailing mother-to-child HIV transmission. By addressing the unique challenges experienced by migrant mothers and their infants, this study contributes significantly to broader efforts in controlling the spread of HIV, ultimately enhancing the health outcomes and well-being of Dongguan's migrant population. Furthermore, our research introduces a distinctive perspective within the extensively examined domain of Prevention of Mother-to-Child Transmission (PMTCT) programs, focusing on the internally migrant Chinese population, an understudied demographic group in this context. This study, conducted in Dongguan, China, represents one of the pioneering investigations into pregnant women with HIV and their infants within this migrant community.
流动人口由从农村地区迁移到城市地区的个人组成，他们面临着独特的挑战，这增加了他们感染艾滋病毒的易感性。这些挑战源于社会人口因素和获得医疗服务的机会有限。了解这一人群中艾滋病毒传播的动态对于制定有效的预防策略至关重要。
为了调查导致流动人口中艾滋病毒易感性的因素，我们于2018年1月1日至2021年12月31日在东莞市人民医院进行了一项横断面研究。我们的研究重点是感染艾滋病毒的孕妇及其婴儿，特别强调社会人口特征、艾滋病毒检测和治疗情况以及新生儿临床数据。使用标准化表格系统地收集数据。
对98名参与者的数据进行分析后发现了值得注意的结果。在年龄、婚姻状况和教育背景与艾滋病毒易感性之间未观察到显著关联。同样，性伴侣状况、配偶治疗和子女数量等因素也没有显著影响。然而，我们的分析强调了艾滋病毒阳性女性治疗策略以及艾滋病毒感染女性开始抗逆转录病毒治疗的时机的关键作用，这两者均与艾滋病毒传播相关（<0.05）。此外，喂养方式、新生儿抗逆转录病毒预防和预防治疗策略等因素显示出显著关联，而新生儿预防治疗方案则未显示出显著影响。
这些发现为东莞流动人口面临的艾滋病毒预防的特定风险因素和障碍提供了宝贵见解。它们强调了旨在减少母婴艾滋病毒传播的有针对性干预措施和政策的重要性。通过应对流动母亲及其婴儿所面临的独特挑战，本研究为控制艾滋病毒传播的更广泛努力做出了重大贡献，最终改善了东莞流动人口的健康状况和福祉。此外，我们的研究在广泛研究的预防母婴传播（PMTCT）项目领域引入了独特视角，重点关注中国国内流动人群，这是在此背景下一个研究较少的人口群体。在中国东莞进行的这项研究是对该流动社区中感染艾滋病毒的孕妇及其婴儿的开创性调查之一。
