Department of Ophthalmology, Zagreb University Hospital Center, Zagreb, Croatia.
University of Zagreb, School of Medicine, Zagreb, Croatia.
Acta Clin Croat. 2022 Dec;61(4):727-734. doi: 10.20471/acc.2022.61.04.22.
We present a patient with concurrent pigmentary glaucoma, bilateral central serous chorioretinopathy and unilateral optic disc pit, and propose a possible association of these conditions. Comprehensive ophthalmic examination of a 36-year-old man who was complaining of blurry vision and pain in the eyes showed reduced visual acuity on the left eye, elevated intraocular pressure in the right eye, bilateral signs of pigment dispersion syndrome, and bilateral central serous chorioretinopathy, combined with optic disc pit in the left eye. Visual field and optical coherence tomography findings demonstrated functional and structural glaucoma changes. Choroidal circulation abnormalities were observed by angiographic methods. Genetic and developmental anomalies of the external layer of the optic disc cup that gives rise to many anterior and posterior eye segment structures suggest a possible association of a clinical condition characterized by the combination of pigmentary glaucoma, central serous chorioretinopathy and optic disc pit. Future research would enable to determine proper diagnostic protocols, treatment and follow-up procedures for this chronic-progressive disorder.
我们报告了一例同时患有色素性青光眼、双侧中心性浆液性脉络膜视网膜病变和单侧视盘小凹的患者,并提出了这些情况可能存在关联的假设。对一名 36 岁男性进行全面眼科检查,该男性主诉视力模糊和眼睛疼痛,结果显示左眼视力下降,右眼眼压升高,双侧色素播散综合征表现,双侧中心性浆液性脉络膜视网膜病变,左眼合并视盘小凹。视野和光学相干断层扫描结果显示出功能性和结构性青光眼改变。通过血管造影方法观察到脉络膜循环异常。视盘杯外皮层的遗传和发育异常导致许多前节和后节结构的产生,提示一种以色素性青光眼、中心性浆液性脉络膜视网膜病变和视盘小凹联合为特征的临床情况可能存在关联。未来的研究将能够确定这种慢性进行性疾病的适当诊断方案、治疗和随访程序。