Grassmeyer Justin J, Bellsmith Kellyn N, Bradee Allison R, Pegany Roma B, Redd Travis K
Casey Eye Institute, Oregon Health & Science University, Portland, OR.
Cornea Open. 2023 Oct 19;2(4):e0022. doi: 10.1097/coa.0000000000000022. eCollection 2023 Dec.
To report and present images of a case in which discrete conjunctival lesions developed in the setting of primary varicella zoster virus infection (ie, chickenpox).
Case report and literature review.
This report describes a young, unvaccinated male who developed an acutely painful, red eye in the setting of disseminated primary varicella zoster infection. The cutaneous rash was widespread and included lesions on both eyelids. The patient was found to have multiple discrete de-epithelialized lesions involving the palpebral and bulbar conjunctiva. Throughout the disease course, good visual function was maintained and there was no evidence of intraocular involvement. The ocular surface lesions resolved without sequelae after 1 week of treatment with topical antibiotic ointment.
Primary varicella zoster infection is an increasingly rare phenomenon in the setting of widespread vaccination. However, unvaccinated or undervaccinated individuals and other at-risk populations remain susceptible to developing severe infections. This case of chickenpox involved discrete conjunctival lesions that resolved without sequelae after conservative treatment with topical antibiotic ointment. While serious ophthalmic complications are uncommon in primary varicella infection, clinicians should be aware of the potential for ocular morbidity in this increasingly rare condition.
报告并展示一例在原发性水痘带状疱疹病毒感染（即水痘）情况下出现离散性结膜病变的病例图像。
病例报告及文献综述。
本报告描述了一名未接种疫苗的年轻男性，在播散性原发性水痘带状疱疹感染时出现急性疼痛、眼红。皮肤皮疹广泛，包括双侧眼睑的病变。患者被发现有多个累及睑结膜和球结膜的离散性脱上皮病变。在整个病程中，视觉功能保持良好，且无眼内受累的证据。经局部抗生素眼膏治疗1周后，眼表病变消退，无后遗症。
在广泛接种疫苗的情况下，原发性水痘带状疱疹感染是一种越来越罕见的现象。然而，未接种疫苗或接种不足的个体以及其他高危人群仍易发生严重感染。该水痘病例累及离散性结膜病变，经局部抗生素眼膏保守治疗后消退，无后遗症。虽然原发性水痘感染中严重的眼科并发症不常见，但临床医生应意识到在这种日益罕见的疾病中存在眼部发病的可能性。
