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应对四种具有挑战性疼痛综合征的当前方法。

Current Approaches to Four Challenging Pain Syndromes.

作者信息

Moka Eleni, Allam Abdallah El-Sayed, Rekatsina Martina, Abed Lynda, Paladini Antonella, AlKharabsheh Abdullah, Vadalouca Athina, Varrassi Giustino

机构信息

Department of Anesthesiology, Creta InterClinic Hospital, Herakleion, GRC.

Morphological Madrid Research Center (MoMaRC), UltraDissection Spain EchoTraining School, Madrid, ESP.

出版信息

Cureus. 2023 Sep 19;15(9):e45573. doi: 10.7759/cureus.45573. eCollection 2023 Sep.

Abstract

During a conference of pain specialists, some of the experts addressed the potential management of four prevalent but difficult painful conditions, namely, chronic postsurgical pain (CPSP), knee osteoarthritis, chest trauma, and facet joint arthropathy. In all cases, the conditions posed challenges in accurate diagnoses as well as safe, effective treatments, especially using locoregional blocks. It is not clear why some surgical patients develop CPSP and others do not, although some risk factors have been identified. More importantly, the transitional phase of pain from acute to chronic deserves greater scrutiny. It appears as if more aggressive and more effective perioperative and postoperative analgesia could help mitigate or possibly prevent CPSP. Knee osteoarthritis is prevalent but is often managed pharmacologically and then with joint replacement; many patients simply live with the condition which can be viewed as a disease of the entire joint. New approaches with intra-articular injections of hyaluronic acid, platelet-rich plasma, and botulinum toxin may provide safe, effective, and durable pain control. Chest trauma can be extremely painful and a source of morbidity, but its management tends to rely on watchful waiting and drug therapy. New approaches to regional nerve blocks can be beneficial and may reduce troublesome symptoms such as the inability to cough or clear the lungs. Facet joint arthropathy is very prevalent among older people but is not completely clarified. It may be the source of intense pain with limited management strategies. The role of nerve blocks in facet joint arthropathy is an important new addition to the armamentarium of pain management, particularly for geriatric patients.

摘要

在一次疼痛专家会议上,一些专家探讨了四种常见但棘手的疼痛病症的潜在治疗方法,即慢性术后疼痛(CPSP)、膝关节骨关节炎、胸部创伤和小关节病。在所有这些病例中,这些病症在准确诊断以及安全、有效的治疗方面都带来了挑战,尤其是在使用局部阻滞时。目前尚不清楚为什么有些手术患者会患上CPSP而有些则不会,尽管已经确定了一些风险因素。更重要的是,疼痛从急性到慢性的过渡阶段值得更深入的研究。似乎更积极、更有效的围手术期和术后镇痛有助于减轻或可能预防CPSP。膝关节骨关节炎很常见,但通常采用药物治疗,然后进行关节置换;许多患者只能忍受这种疾病,它可被视为一种累及整个关节的病症。关节腔内注射透明质酸、富血小板血浆和肉毒杆菌毒素的新方法可能提供安全、有效且持久的疼痛控制。胸部创伤可能极其疼痛,且是发病的一个原因,但其治疗往往依赖于密切观察和药物治疗。区域神经阻滞的新方法可能有益,并可能减轻诸如无法咳嗽或清除肺部痰液等令人烦恼的症状。小关节病在老年人中非常普遍,但尚未完全明确。它可能是剧烈疼痛的根源,而治疗策略有限。神经阻滞在小关节病治疗中的作用是疼痛治疗手段中的一项重要新补充,尤其对于老年患者而言。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99e7/10586888/c194179f66c0/cureus-0015-00000045573-i01.jpg

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