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真皮中层弹性组织溶解症病例报告:颈部的一种独特表现

A Case Report on Mid-Dermal Elastolysis: A Distinctive Presentation on the Neck.

作者信息

Aryal Sabita, Li Yaoyu, Bashyal Subodh, Qiang Liu Ye, Rehman Abdur

机构信息

Department of Dermatology, Shanghai Skin Disease Hospital, Tongji University, Shanghai, CHN.

Department of Endocrinology and Metabolism, Tenth People's Hospital, Tongji University, Shanghai, CHN.

出版信息

Cureus. 2023 Sep 21;15(9):e45724. doi: 10.7759/cureus.45724. eCollection 2023 Sep.

DOI:10.7759/cureus.45724
PMID:37868427
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10590218/
Abstract

Mid-dermal elastolysis (MDE) is a very rare and acquired skin condition. MDE has a variety of clinical manifestations that can be presented with a reticular erythematous patch with telangiectasis, perifollicular popular protrusions, or finely wrinkled skin. A biopsy is always necessary to rule out other potential elastic fiber disorders. In this case study, a 33-year-old female with an odd MDE presentation in her neck area is examined. No contributing factors, apart from exposure to sunlight, could be gleaned from the patient's history. The patient didn't benefit from the application of various types of topical agents or any other therapies to lessen the size and advancement of the lesion. In this distinct case, we discuss clinical and histological findings and the treatment plan offered, as well as include a concise review of specific past literature.

摘要

真皮中层弹性纤维溶解症(MDE)是一种非常罕见的后天性皮肤病。MDE有多种临床表现,可表现为伴有毛细血管扩张的网状红斑、毛囊周围丘疹样突起或皮肤细纹。活检对于排除其他潜在的弹性纤维疾病总是必要的。在本病例研究中,对一名颈部出现奇特MDE表现的33岁女性进行了检查。除了暴露于阳光下外,从患者病史中未发现其他相关因素。患者使用各种外用药物或任何其他疗法来减轻病变的大小和进展均无效果。在这个独特的病例中,我们讨论了临床和组织学发现以及提供的治疗方案,并对既往的特定文献进行了简要综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f3/10590218/b26bff7c9fb7/cureus-0015-00000045724-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f3/10590218/d1dd9cd8c2d8/cureus-0015-00000045724-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f3/10590218/73db5a3ea9d0/cureus-0015-00000045724-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f3/10590218/b26bff7c9fb7/cureus-0015-00000045724-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f3/10590218/d1dd9cd8c2d8/cureus-0015-00000045724-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f3/10590218/73db5a3ea9d0/cureus-0015-00000045724-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f3/10590218/b26bff7c9fb7/cureus-0015-00000045724-i03.jpg

相似文献

1
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本文引用的文献

1
Mid-Dermal Elastolysis: A Case Report and Literature Review.真皮中层弹性组织溶解症:一例报告及文献综述
Indian J Dermatol. 2023 Mar-Apr;68(2):217-219. doi: 10.4103/ijd.ijd_957_22.
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Dermal extracellular matrix molecules in skin development, homeostasis, wound regeneration and diseases.皮肤发育、稳态、创伤再生和疾病中的真皮细胞外基质分子。
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Skin wrinkling of the upper arms: a case of mid-dermal elastolysis.上臂皮肤起皱:一例真皮中部弹性组织离解症。
Dermatol Online J. 2020 Apr 15;26(4):13030/qt1ws2x7fg.
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Cutaneous Elastic Tissue Anomalies.皮肤弹性组织异常
Am J Dermatopathol. 2019 Feb;41(2):85-117. doi: 10.1097/DAD.0000000000001275.
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Mid-dermal elastolysis: A female-centric disease; case report and updated review of the literature.真皮中层弹性组织离解:一种以女性为中心的疾病;病例报告及文献综述更新
Int J Womens Dermatol. 2015 Jul 26;1(3):126-130. doi: 10.1016/j.ijwd.2015.05.004. eCollection 2015 Aug.
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Mid-dermal elastolysis revisited.真皮中层弹力纤维溶解症再探。
Arch Dermatol Res. 2010 Mar;302(2):85-93. doi: 10.1007/s00403-009-1004-0.
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Mid-dermal elastolysis: a clinical, histologic, and immunohistochemical study of 11 patients.真皮中层弹性纤维溶解症:11例患者的临床、组织学及免疫组织化学研究
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J Am Acad Dermatol. 1993 Jun;28(6):938-42. doi: 10.1016/0190-9622(93)70134-f.
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Br J Dermatol. 1994 Apr;130(4):502-6. doi: 10.1111/j.1365-2133.1994.tb03386.x.
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Structure of the elastic fiber: an overview.弹性纤维的结构:概述
J Invest Dermatol. 1982 Jul;79 Suppl 1:128s-132s. doi: 10.1111/1523-1747.ep12546005.