Stacul F, Magnaldi S, Pozzi-Mucelli R, Muner G, Dalla Palma L
Radiol Med. 1986 Nov;72(11):815-22.
Nonionic contrast media (cm) are more and more widely employed in vascular radiology. These cm are the choice in some conventional arteriographies owing to their better tolerability. In intravenous digital subtraction angiography (DSA) the analysis of the personal material and of the literature allows to state that: the image quality with ionic and non ionic cm is similar; the tolerability of nonionic cm is slightly superior; the cardiac and renal toxicity of nonionic cm is slightly lower; reactions to nonionic cm take place with a lower frequency; the price of nonionic cm is considerably higher. Therefore nonionic cm seem to be slightly superior to ionic agents on the basis of these data and they should be theoretically preferred. The only doubt to their routine use in intravenous DSA is the high cost. Therefore we prefer to employ them in risk patients only, as ionic cm in current use are safe and cheap.
非离子型造影剂（CM）在血管放射学中的应用越来越广泛。由于其更好的耐受性，这些CM在一些传统动脉造影中是首选。在静脉数字减影血管造影（DSA）中，对个人资料和文献的分析表明：离子型和非离子型CM的图像质量相似；非离子型CM的耐受性略优；非离子型CM的心脏和肾脏毒性略低；对非离子型CM的反应发生频率较低；非离子型CM的价格要高得多。因此，基于这些数据，非离子型CM似乎略优于离子型造影剂，理论上应优先选择。对其在静脉DSA中常规使用的唯一疑虑是成本高昂。因此，我们仅在高危患者中使用它们，因为目前使用的离子型CM安全且便宜。
