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脑淀粉样血管病相关性炎症:一例报告及文献综述

Cerebral Amyloid Angiopathy-Related Inflammation: A Case Report and Literature Review.

作者信息

Park Chanjin, Choi Eun Sun, Kim Eunhee

出版信息

J Korean Soc Radiol. 2023 Sep;84(5):1140-1145. doi: 10.3348/jksr.2022.0113. Epub 2023 Aug 9.

Abstract

Cerebral amyloid angiopathy-related inflammation (CAA-RI) is an encephalopathy caused by inflammation of β-amyloid peptide deposition in cerebrovascular vessels. It is a rare disease that mainly occurs in the elderly and is characterized by rapidly progressive dementia, headache, seizures, and focal neurologic deficits. CAA-RI can demonstrate characteristic brain MRI findings and can be reversed by steroids or other immunosuppressive therapies. Here, we report a case of CAA-RI, which was initially misdiagnosed as a subacute infarction but was diagnosed while reviewing follow-up brain MRI images, and spontaneous remission was achieved.

摘要

脑淀粉样血管病相关性炎症(CAA-RI)是一种由脑血管中β淀粉样肽沉积引发炎症所致的脑病。它是一种罕见疾病,主要发生于老年人,其特征为快速进展性痴呆、头痛、癫痫发作和局灶性神经功能缺损。CAA-RI可表现出特征性的脑部MRI表现,并且可通过类固醇或其他免疫抑制疗法得到缓解。在此,我们报告一例CAA-RI病例,该病例最初被误诊为亚急性梗死,但在复查脑部MRI随访图像时得以确诊,并实现了自发缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c4a/10585078/c4af7ea1817d/jksr-84-1140-g001.jpg

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