Yang Mi Hyun, Kim Eun Hee, Choi Eun Sun, Ko Hongseok
J Korean Soc Radiol. 2023 Sep;84(5):1080-1090. doi: 10.3348/jksr.2023.0006. Epub 2023 Sep 22.
This study aimed to compare the volume and normative percentiles of brain volumetry in the Korean population using quantitative brain volumetric MRI analysis tools NeuroQuant (NQ) and DeepBrain (DB), and to evaluate whether the differences in the normative percentiles of brain volumetry between the two tools is related to cranial shape.
In this retrospective study, we analyzed the brain volume reports obtained from NQ and DB in 163 participants without gross structural brain abnormalities. We measured three-dimensional diameters to evaluate the cranial shape on T1-weighted images. Statistical analyses were performed using intra-class correlation coefficients and linear correlations.
The mean normative percentiles of the thalamus (90.8 vs. 63.3 percentile), putamen (90.0 vs. 60.0 percentile), and parietal lobe (80.1 vs. 74.1 percentile) were larger in the NQ group than in the DB group, whereas that of the occipital lobe (18.4 vs. 68.5 percentile) was smaller in the NQ group than in the DB group. We found a significant correlation between the mean normative percentiles obtained from the NQ and cranial shape: the mean normative percentile of the occipital lobe increased with the anteroposterior diameter and decreased with the craniocaudal diameter.
The mean normative percentiles obtained from NQ and DB differed significantly for many brain regions, and these differences may be related to cranial shape.
本研究旨在使用定量脑容积磁共振成像分析工具NeuroQuant（NQ）和DeepBrain（DB）比较韩国人群脑容积测定的体积和正常百分位数，并评估两种工具之间脑容积测定正常百分位数的差异是否与颅骨形状有关。
在这项回顾性研究中，我们分析了163名无明显脑结构异常参与者从NQ和DB获得的脑容积报告。我们在T1加权图像上测量三维直径以评估颅骨形状。使用组内相关系数和线性相关性进行统计分析。
NQ组丘脑（90.8百分位数对63.3百分位数）、壳核（90.0百分位数对60.0百分位数）和顶叶（80.1百分位数对74.1百分位数）的平均正常百分位数大于DB组，而NQ组枕叶（18.4百分位数对68.5百分位数）的平均正常百分位数小于DB组。我们发现从NQ获得的平均正常百分位数与颅骨形状之间存在显著相关性：枕叶的平均正常百分位数随前后径增加而增加，随颅尾径增加而减小。
从NQ和DB获得的许多脑区的平均正常百分位数存在显著差异，这些差异可能与颅骨形状有关。
