Internal Medicine Service, University General Hospital of Castellon, Castellón de la Plana, Spain.
Internal Medicine Service, Hospital of Vinaroz, Vinaroz, Spain.
Front Public Health. 2023 Oct 6;11:1236527. doi: 10.3389/fpubh.2023.1236527. eCollection 2023.
The long-term effects of SARS-CoV-2 are unclear, as are the factors influencing the evolution. Objective: to assess health-related quality of life 1 year after a hospital admission due to COVID-19 and to identify factors that may influence it.
Retrospective observational study in a tertiary hospital from March 2021 to February 2022. Inclusion criteria: ≥18 years old and admitted for SARS-CoV-2 infection. Exclusion criteria: death, not located, refusal to participate, cognitive impairment, and language barrier. Variables: demographic data, medical history, clinical and analytical outcomes during hospital admission, treatment received, and vaccination against SARS-CoV-2 following admission. Participants were interviewed by phone 1 year after admission, using the SF-36 quality of life questionnaire.
There were 486 included patients. The domains yielding the lowest scores were general health (median 65%, interquartile range [IQR] 45-80), vitality (median 65%, IQR 45-80), and mental health (median 73.5%, IQR 60-100). Multivariable analysis showed that female sex and fibromyalgia/fatigue had a negative influence on all domains. Obesity was associated with worse outcomes in physical functioning, physical role, bodily pain, and vitality. Other factors associated with worse scores were an older age in physical functioning and high age-adjusted Charslon comorbidity in physical functioning and general health. Age was associated with better results in emotional role and High C-reactive protein at admission on vitality.
One year after admission for COVID-19, quality of life remains affected, especially the domains of general health, vitality, and mental health. Factors associated with worse outcomes are female sex, fibromyalgia/chronic fatigue, and obesity.
SARS-CoV-2 的长期影响尚不清楚，影响其演变的因素也不清楚。目的：评估因 COVID-19 住院 1 年后与健康相关的生活质量，并确定可能影响其的因素。
这是 2021 年 3 月至 2022 年 2 月在一家三级医院进行的回顾性观察研究。纳入标准：≥18 岁，因 SARS-CoV-2 感染住院。排除标准：死亡、未找到、拒绝参与、认知障碍和语言障碍。变量：人口统计学数据、病史、住院期间的临床和分析结果、接受的治疗以及住院后接种 SARS-CoV-2 疫苗。在出院 1 年后，通过电话对参与者进行采访，使用 SF-36 生活质量问卷。
共纳入 486 例患者。得分最低的领域是一般健康（中位数 65%，四分位距 [IQR] 45-80）、活力（中位数 65%，IQR 45-80）和心理健康（中位数 73.5%，IQR 60-100）。多变量分析显示，女性和纤维肌痛/疲劳对所有领域均有负面影响。肥胖与身体机能、身体角色、身体疼痛和活力的结果较差有关。与较差评分相关的其他因素包括身体机能中的年龄较大和身体机能及一般健康中的年龄调整 Charlson 合并症较高。年龄与入院时高 C 反应蛋白对活力的情绪角色和高 C 反应蛋白呈正相关。
COVID-19 住院 1 年后，生活质量仍受影响，尤其是一般健康、活力和心理健康领域。与较差结果相关的因素是女性、纤维肌痛/慢性疲劳和肥胖。
