Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Villa Roberto Edoardo, Woutersen Ruud, Ortuño Casanova Jordi, Pettenati Elisa
EFSA J. 2023 Oct 19;21(10):e08354. doi: 10.2903/j.efsa.2023.8354. eCollection 2023 Oct.
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of viable cells of DSM 33761, DSM 33758, DSM 16284, DSM 33751 and DSM 16351 (Biomin® C5) as a zootechnical additive (functional group: gut flora stabiliser) for chickens for fattening, chickens reared for laying, turkeys for fattening, turkeys reared for breeding and minor poultry species for fattening and reared for laying/breeding. Biomin® C5 is marketed in two formulations: a coated and a non-coated formulation with a total minimum microbial count of 1 × 10 and 4 × 10 colony forming unit (CFU)/g product, respectively. The Panel considered that the use of Biomin® C5 in feed at the proposed conditions of use raises no risk for the target species, consumers and the environment. Both coated and non-coated formulations of Biomin® C5 are considered respiratory and skin sensitisers, but not skin irritants. The FEEDAP Panel was not in the position to conclude on the eye irritation potential of any formulation. Due to lack of sufficient data, the FEEDAP Panel could not conclude on the efficacy of the additive in the target species at the proposed conditions of use. Biomin® C5 is compatible with nicarbazin, diclazuril, decoquinate and halofuginone. No conclusions can be drawn on the compatibility of Biomin® C5 with monensin sodium, robenidine hydrochloride, maduramicin ammonium and lasalocid A sodium.
应欧盟委员会的要求,动物饲料添加剂及产品或物质专家小组(FEEDAP)被要求就一种饲料添加剂的安全性和有效性发表科学意见,该添加剂由DSM 33761、DSM 33758、DSM 16284、DSM 33751和DSM 16351(Biomin® C5)的活细胞组成,用作育肥鸡、产蛋鸡、育肥火鸡、种用火鸡以及育肥和产蛋/育种小型家禽的动物技术添加剂(功能组:肠道菌群稳定剂)。Biomin® C5有两种剂型上市:一种包衣剂型和一种非包衣剂型,产品的总最低微生物计数分别为1×10和4×10菌落形成单位(CFU)/克。专家小组认为,在建议的使用条件下,在饲料中使用Biomin® C5对目标物种、消费者和环境没有风险。Biomin® C5的包衣和非包衣剂型均被视为呼吸道和皮肤致敏剂,但不是皮肤刺激物。FEEDAP专家小组无法就任何剂型的眼刺激潜力得出结论。由于缺乏足够的数据,FEEDAP专家小组无法就该添加剂在建议的使用条件下对目标物种的有效性得出结论。Biomin® C5与尼卡巴嗪、地克珠利、癸氧喹酯和常山酮相容。关于Biomin® C5与莫能菌素钠、盐酸氯苯胍、马杜霉素铵和拉沙洛西钠A的相容性无法得出结论。