Watrigant Y, Wallaert B, Ramon P, Gosselin B, Peng W, Tonnel A B
Rev Mal Respir. 1986;3(4):227-9.
We report a case of diffuse interstitial pulmonary disease in a 73 year old woman treated for moderate hypertension for one year with the combination of hydrochlorothiazide (50 mg/day) and Amiloride (5 mg/day). The bronchoalveolar lavage showed a neutrophilia of 23% and a 5.5% eosinophilia. The absence of any other aetiological factor and the favourable outcome on cessation of the sole medication incriminate the latter as an aetiological agent in this interstitial pneumonitis.
我们报告了一例73岁女性的弥漫性间质性肺疾病，该患者因中度高血压接受氢氯噻嗪（50毫克/天）和阿米洛利（5毫克/天）联合治疗一年。支气管肺泡灌洗显示中性粒细胞增多达23%，嗜酸性粒细胞增多达5.5%。由于不存在任何其他病因因素，且停用唯一可疑药物后病情出现好转，因此认定该药物是此次间质性肺炎的病因。
