Cambaz Kurt N, Kutlu N O
Department of Pediatrics, Istanbul, University of Health Science, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Eur Rev Med Pharmacol Sci. 2023 Oct;27(5 Suppl):53-61. doi: 10.26355/eurrev_202310_34070.
Anaphylaxis is a severe hypersensitivity reaction with a rapid onset and is potentially life-threatening if not treated promptly. This study aimed to determine the level of knowledge of pediatricians in Turkey in recognizing and treating the clinical symptoms of anaphylaxis, compare the previous studies conducted in Turkey chronologically, and show the current trends on awareness of anaphylaxis in developed and developing countries in the world.
Pediatric residents and specialists from all over Turkey were included in the study. A questionnaire was prepared by compiling the current literature. Questions were sent to pediatricians via online applications. Statistical tests were used to analyze the data.
A total of 524 pediatricians participated in the study. All participants accepted that anaphylaxis was a life-threatening condition. Almost all suggested epinephrine as the primary drug used in anaphylaxis. The proportion of pediatricians who knew the appropriate dose, route of administration, and place of administration of epinephrine was 82.8%, 88.9%, and 89.7%, respectively. The rate of pediatricians who recognized the clinical features of anaphylaxis was over 90%. The proportion of pediatricians who knew the epinephrine auto-injector and dose was 74.4% and 53.1%, respectively. Pediatricians with less than 10 years of experience and those working in public hospitals had better knowledge about atypical symptoms of anaphylaxis.
Although there are still inadequacies in identifying atypical symptoms and treating anaphylaxis, our study revealed that the level of awareness of anaphylaxis had shown an increasing trend in Turkey over time. On the other hand, the knowledge on diagnosing and treating anaphylaxis still needs to be improved, especially for physicians working in rural areas of developing countries.
过敏反应是一种起病迅速的严重超敏反应，若不及时治疗可能危及生命。本研究旨在确定土耳其儿科医生对过敏反应临床症状的识别和治疗知识水平，按时间顺序比较此前在土耳其开展的研究，并展示世界上发达国家和发展中国家对过敏反应的认知现状。
纳入来自土耳其各地的儿科住院医师和专科医生。通过汇编当前文献编制了一份问卷。问题通过在线应用程序发送给儿科医生。使用统计测试分析数据。
共有524名儿科医生参与了该研究。所有参与者都承认过敏反应是一种危及生命的疾病。几乎所有人都建议将肾上腺素作为过敏反应的主要用药。知道肾上腺素合适剂量、给药途径和给药部位的儿科医生比例分别为82.8%、88.9%和89.7%。识别过敏反应临床特征的儿科医生比例超过90%。知道肾上腺素自动注射器及其剂量的儿科医生比例分别为74.4%和53.1%。经验少于10年的儿科医生以及在公立医院工作的儿科医生对过敏反应非典型症状的了解更好。
尽管在识别非典型症状和治疗过敏反应方面仍存在不足，但我们的研究表明，随着时间推移，土耳其对过敏反应的认知水平呈上升趋势。另一方面，尤其是发展中国家农村地区的医生，在过敏反应诊断和治疗方面的知识仍需改进。
