将提高身体机能作为心绞痛患者的治疗目标。
Improved physical performance as a therapeutic objective in patients with angina.
作者信息
Ling A S, Groel J T
出版信息
Br J Clin Pharmacol. 1979;7 Suppl 2(Suppl 2):161S-166S. doi: 10.1111/j.1365-2125.1979.tb04686.x.
Abstract
1 Improvement in physical performance, based on exercise tolerance, self-assessed work and physician-rated functional capacities, is proposed as a measure of efficacy of anti-anginal therapy in the rehabilitation of the cardiac patient. 2 Improved physical performance parallels changes in frequency of anginal attacks and a nitroglycerin requirements following beta-blocker therapy. 3 Nadolol (a beta-blocker), given once daily is as effective as propranolol, given four times daily as an anti-anginal agent.
摘要
- 基于运动耐量、自我评估的工作能力和医生评定的功能能力的身体机能改善，被提议作为衡量抗心绞痛治疗对心脏病患者康复疗效的一项指标。2. 身体机能的改善与β受体阻滞剂治疗后心绞痛发作频率及硝酸甘油需求量的变化相似。3. 作为一种抗心绞痛药物，每日服用一次的纳多洛尔（一种β受体阻滞剂）与每日服用四次的普萘洛尔效果相同。
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Improved physical performance as a therapeutic objective in patients with angina.将提高身体机能作为心绞痛患者的治疗目标。
Br J Clin Pharmacol. 1979;7 Suppl 2(Suppl 2):161S-166S. doi: 10.1111/j.1365-2125.1979.tb04686.x.
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本文引用的文献
1
A NEW ADRENERGIC BETARECEPTOR ANTAGONIST.一种新型肾上腺素能β受体拮抗剂。
Lancet. 1964 May 16;1(7342):1080-1. doi: 10.1016/s0140-6736(64)91275-9.
2
Clinical pharmacology of a beta-adrenergic-blocking agent (Nethalide).一种β-肾上腺素能阻滞剂（奈他洛尔）的临床药理学
Lancet. 1962 Aug 18;2(7251):314-6. doi: 10.1016/s0140-6736(62)90104-6.
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Propranolol metabolism in man and dog: mass spectrometric identification of six new metabolites.普萘洛尔在人和犬体内的代谢：六种新代谢物的质谱鉴定
J Pharmacol Exp Ther. 1972 Jul;182(1):83-92.
4
Some comments and reflections on changing interests and new developments in angina pectoris.关于心绞痛兴趣变化与新进展的一些评论和思考。
Circulation. 1972 Dec;46(6):1037-47. doi: 10.1161/01.cir.46.6.1037.
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Pharmacokinetic studies of practolol, a beta adrenergic antagonist, in man.β肾上腺素能拮抗剂心得宁在人体的药代动力学研究。
Clin Pharmacol Ther. 1973 Jan-Feb;14(1):26-9. doi: 10.1002/cpt197314126.
6
Comparison of adrenergic beta-blocking drugs in angina pectoris.肾上腺素能β受体阻滞剂在心绞痛治疗中的比较。
Br Med J. 1971 Jul 17;3(5767):152-5. doi: 10.1136/bmj.3.5767.152.
7
Exercise tolerance and physical training of non-selected patients after myocardial infarction.
Acta Med Scand Suppl. 1973;551:1-124.
8
Hypertension and compliance: implications for the primary physician.高血压与依从性：对基层医生的启示
N Engl J Med. 1976 May 13;294(20):1120-1. doi: 10.1056/NEJM197605132942015.
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N Engl J Med. 1975 Aug 7;293(6):280-5. doi: 10.1056/NEJM197508072930606.
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Postgrad Med. 1976 Jul;60(7):81-5. doi: 10.1080/00325481.1976.11714415.
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