Ling A S, Groel J T
Br J Clin Pharmacol. 1979;7 Suppl 2(Suppl 2):161S-166S. doi: 10.1111/j.1365-2125.1979.tb04686.x.
1 Improvement in physical performance, based on exercise tolerance, self-assessed work and physician-rated functional capacities, is proposed as a measure of efficacy of anti-anginal therapy in the rehabilitation of the cardiac patient. 2 Improved physical performance parallels changes in frequency of anginal attacks and a nitroglycerin requirements following beta-blocker therapy. 3 Nadolol (a beta-blocker), given once daily is as effective as propranolol, given four times daily as an anti-anginal agent.