Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Infect Disord Drug Targets. 2024;24(2):e201023222451. doi: 10.2174/0118715265250557231011065142.
Caused by an imbalance in the vaginal microbiome, bacterial vaginosis (BV) is among the most commonly occurring vaginal infections in women of childbearing age. If untreated, BV may have a detrimental impact on the obstetric and gynecological health of an individual. To date, treatment for BV includes a regimen of antibiotics and avoidance of relevant risk factors. Since recurrence and reinfection are frequently observed in patients, pharmaceutical treatment for BV remains ineffective nevertheless. Repeated exposure to antibiotics could precipitate drug-resistant strains. The severity of this problem leads to the emergence of non-antimicrobial therapies. This article aims to provide a review on the types and efficacy of various alternative, non-antimicrobial therapeutic regimens.
细菌性阴道病(BV)是由阴道微生物群失衡引起的,是育龄妇女最常见的阴道感染之一。如果不治疗,BV 可能对个体的产科和妇科健康产生不利影响。迄今为止,BV 的治疗包括抗生素治疗方案和避免相关的危险因素。由于患者经常出现复发和再感染,因此 BV 的药物治疗仍然无效。反复接触抗生素可能会引发耐药菌株。这个问题的严重性导致了非抗菌疗法的出现。本文旨在综述各种替代的、非抗菌治疗方案的类型和疗效。