Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York.
Department of Psychology and at the Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat Gan, Israel.
Bull Menninger Clin. 2023 Spring;87(Supplement A):113-132. doi: 10.1521/bumc.2023.87.suppA.113.
While clinical research on disgust relies on nonclinical research, the framework of disgust as an immune mechanism is not as central in clinical research. The immune framework for disgust may be integrated into clinical research by acknowledging the role of the self as the critical element protected by the immune system. In this review, we offer the premise that at the center of all disgust-related behaviors, thoughts, and cognitions is an attempt to protect the self (i.e., "disgust is self-centered" or DISC). We offer evidence in support of DISC and explore the relevance of DISC to clinical research for several disgust-related psychopathologies (obsessive-compulsive disorder, posttraumatic stress disorder, anorexia nervosa, and self-disgust). We then offer future directions for DISC research into disgust-related psychopathologies.
虽然对厌恶感的临床研究依赖于非临床研究，但将厌恶感视为免疫机制的框架在临床研究中并不那么重要。通过承认自我是免疫系统保护的关键要素，可以将厌恶感的免疫框架纳入临床研究。在这篇综述中，我们提出了这样一个前提，即所有与厌恶感相关的行为、思想和认知的核心都是试图保护自我（即“厌恶感以自我为中心”或 DISC）。我们提供了支持 DISC 的证据，并探讨了 DISC 与几种与厌恶感相关的精神病理学（强迫症、创伤后应激障碍、神经性厌食症和自我厌恶）的临床研究的相关性。然后，我们为 DISC 对与厌恶感相关的精神病理学的研究提供了未来的方向。
