Briheim G, Stendahl O, Dahlgren C
Scand J Haematol. 1986 Sep;37(3):253-8. doi: 10.1111/j.1600-0609.1986.tb02306.x.
This report analyses the locomotory capacity of polymorphonuclear leucocytes (PMNL) isolated from 7 patients with bacterial meningitis. 7 healthy control subjects were also investigated in parallel. It was found that PMNL from the patients suffering from meningitis, isolated both from peripheral blood and from the cerebrospinal fluid, had lost their ability to respond chemotactically to activated serum but not to the chemotactic peptide f-Met-Leu-Phe. The normal chemotactic responsiveness of blood PMNL was restored once the patients recovered from infection.
本报告分析了从7例细菌性脑膜炎患者中分离出的多形核白细胞（PMNL）的运动能力。同时对7名健康对照者进行了平行研究。结果发现，从脑膜炎患者外周血和脑脊液中分离出的PMNL，对活化血清失去了趋化反应能力，但对趋化肽f-Met-Leu-Phe仍有反应。患者从感染中康复后，血液中PMNL的正常趋化反应性得以恢复。
