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利用散斑分析和通过正交泵浦模式投影进行分辨率增强的全光学光声成像。

Full-optical photoacoustic imaging using speckle analysis and resolution enhancement by orthogonal pump patterns projection.

作者信息

Vorobev Viktor, Weidmann David, Agdarov Sergey, Beiderman Yafim, Shabairou Nadav, Benyamin Matan, Klämpfl Florian, Schmidt Michael, Gorin Dmitry, Zalevsky Zeev

机构信息

Center for Photonic Science and Engineering, Skolkovo Innovation Center, Skolkovo Institute of Science and Technology, Moscow, Russia, 143026.

Faculty of Engineering, Bar-Ilan University, 52900, Ramat-Gan, Israel.

出版信息

Sci Rep. 2023 Oct 23;13(1):18081. doi: 10.1038/s41598-023-45490-9.

Abstract

This paper presents an approach for achieving full optical photoacoustic imaging with enhanced resolution utilizing speckle pattern analysis. The proposed technique involves projecting patterns derived from binary masks corresponding to orthogonal functions onto the target to elicit a photoacoustic signal. The resulting signal is then recorded using a high-speed camera and analyzed using correlation analysis of the speckle motion. Our results demonstrate the feasibility of this optical approach to achieve imaging with enhanced resolution without the need for physical contact with the target, opening up new possibilities for non-invasive medical imaging and other applications.

摘要

本文提出了一种利用散斑图案分析实现具有更高分辨率的全光学光声成像方法。所提出的技术包括将源自对应于正交函数的二元掩模的图案投射到目标上,以引发光声信号。然后使用高速相机记录所得信号,并通过散斑运动的相关性分析进行分析。我们的结果证明了这种光学方法在无需与目标进行物理接触的情况下实现高分辨率成像的可行性,为无创医学成像和其他应用开辟了新的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4b7/10593755/a5dcc03b4ced/41598_2023_45490_Fig1_HTML.jpg

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