Lee Gwang-Hoon, Jo Woori, Park Joon-Suk, Kang Tae-Ku, Sung Soo-Eun, Oh Taeho, Kim KilSoo
Preclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, 41061, Republic of Korea.
Department of Veterinary Internal Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu, 41566, Republic of Korea.
Lab Anim Res. 2023 Oct 24;39(1):24. doi: 10.1186/s42826-023-00170-7.
The importance of animal welfare is being recognized worldwide. Recently, the increasing demand for enhanced laboratory animal welfare has led to clinically featured transformations of animal research institutes. This study aims to describe the process and findings of veterinary medical check-ups and its influence on laboratory dogs and pigs welfare. Regular medical checkups were conducted by the attending veterinarian twice a year to ensure the health and welfare of dogs and pigs in our animal research institute. Based on the findings from the medical checkup, we assessed the current health of dogs and pigs,providing reasonable treatments to prevent the risk of complications.
Blood tests and physical examinations revealed clinically relevant findings. Some of these findings were due to insufficient postoperative care after invasive surgical experiments and the remaining were predictable side effects after surgical experiments. However, one finding involved severe gum bleeding due to retained deciduous teeth. This animal was euthanized because it was judged to reach the humane endpoint. Majority of the dogs and pigs at our animal research institute were considered to be healthy, based on the comprehensive results of the medical checkups.
Regular medical checkups by the attending veterinarian established enhanced animal welfare, ensuring the accuracy and reproducibility of animal studies. This pioneering veterinary animal care program can serve as a potential advanced guideline for animal research institutes to improve dogs and pigs welfare.
动物福利的重要性正在全球范围内得到认可。最近,对提高实验动物福利的需求不断增加,导致动物研究机构在临床特征方面发生了转变。本研究旨在描述兽医体检的过程和结果及其对实验犬和猪福利的影响。主治兽医每年对我们动物研究所的犬和猪进行两次定期体检,以确保它们的健康和福利。根据体检结果,我们评估了犬和猪的当前健康状况,提供合理治疗以预防并发症风险。
血液检查和体格检查发现了具有临床意义的结果。其中一些结果是由于侵入性外科实验后术后护理不足,其余的是外科实验后可预测的副作用。然而,有一个结果是由于乳牙滞留导致严重牙龈出血。这只动物被安乐死,因为它被判定达到了人道终点。根据体检的综合结果,我们动物研究所的大多数犬和猪被认为是健康的。
主治兽医进行的定期体检提高了动物福利,确保了动物研究的准确性和可重复性。这个开创性的兽医动物护理计划可以作为动物研究机构改善犬和猪福利的潜在先进指南。