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儿科病房使用鼻持续气道正压通气(Nasal CPAP)能否减少因重症细支气管炎而入住儿科重症监护病房(PICU)的人数?

Nasal CPAP in the Pediatric Ward to Reduce PICU Admissions for Severe Bronchiolitis?

作者信息

Aricò Melodie O, Wrona Diana, Lavezzo Giovanni, Valletta Enrico

机构信息

Department of Pediatrics, G.B. Morgagni-L. Pierantoni Hospital, AUSL Romagna, 48018 Forli, Italy.

School of Specialization in Pediatrics, University of Bologna, 40138 Bologna, Italy.

出版信息

Pediatr Rep. 2023 Oct 13;15(4):599-607. doi: 10.3390/pediatric15040055.

Abstract

In treating acute bronchiolitis in infants, the decision to use continuous positive airway pressure (CPAP) often involves infant referral from the pediatric ward to the pediatric intensive care unit (PICU). We present our experience of CPAP use in a general pediatric ward, aiming to reduce the pressure on the PICU in recent outbreaks of bronchiolitis. Clinical data of patients less than 12 months of age and admitted for bronchiolitis from 1 October 2021 to 31 March 2023 were retrospectively collected. Of 82 infants admitted for bronchiolitis, 16 (19%) were treated with nasal CPAP (nCPAP group); of the remaining 66, 21 (26%) were treated with a low-flow nasal cannula (LFNC) only, 1 (1%) was also treated a with high-flow nasal cannula (HFNC), 12 (15%) were treated with an HFNC only, and 41 (50%) were treated without oxygen support (no-nCPAP group). Overall, coinfection with RSV and SARS-CoV-2 was observed in three patients and SARS-CoV-2 infection was observed in two patients. None of them required any type of oxygen support. Only 3/16 (19%) infants in the nCPAP group were referred to the PICU due to worsening clinical conditions despite nCPAP support. In our experience of treating epidemic bronchiolitis, nCPAP can be safely managed in a general pediatric ward, thus reducing the burden of admissions to the PICU. Training and regular updating of the pediatric staff, careful monitoring of the patient, and close cooperation with the PICU were instrumental for our team.

摘要

在治疗婴儿急性细支气管炎时,决定使用持续气道正压通气(CPAP)通常涉及将婴儿从儿科病房转诊至儿科重症监护病房(PICU)。我们介绍了在普通儿科病房使用CPAP的经验,旨在减轻近期细支气管炎暴发期间PICU的压力。回顾性收集了2021年10月1日至2023年3月31日因细支气管炎入院的12个月以下患者的临床资料。在82例因细支气管炎入院的婴儿中,16例(19%)接受了鼻CPAP治疗(nCPAP组);其余66例中,21例(26%)仅接受了低流量鼻导管吸氧(LFNC),1例(1%)还接受了高流量鼻导管吸氧(HFNC),12例(15%)仅接受了HFNC治疗,41例(50%)未接受氧疗(非nCPAP组)。总体而言,3例患者同时感染了呼吸道合胞病毒(RSV)和严重急性呼吸综合征冠状病毒2(SARS-CoV-2),2例患者感染了SARS-CoV-2。他们均无需任何类型的氧疗。nCPAP组中仅有3/16(19%)的婴儿尽管接受了nCPAP支持,但因临床病情恶化被转诊至PICU。根据我们治疗流行性细支气管炎的经验,nCPAP可在普通儿科病房安全管理,从而减轻PICU的收治负担。儿科工作人员的培训和定期更新、对患者的仔细监测以及与PICU的密切合作对我们团队很有帮助。

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