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体外生命支持中的辐射暴露。

Radiation Exposure in Extracorporeal Life Support.

机构信息

From the Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.

Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio.

出版信息

ASAIO J. 2023 Dec 1;69(12):1049-1054. doi: 10.1097/MAT.0000000000002037. Epub 2023 Oct 24.

Abstract

Extracorporeal membrane oxygenation (ECMO) exposes patients to multiple radiologic studies. We hypothesized ECMO patients endure radiation exposure in excess of the International Commission of Radiological Protection (ICRP) recommendations of cumulative effective dose (CED, >20 mSv and 5-year cumulative limit of CED >100 mSv). We conducted a retrospective observational study in an academic medical center between January 2016 and December 2018 involving adult admissions (N = 306) on ECMO. Ionizing radiation was calculated from reference values to determine CED. Approximately 9.4% (N = 29) patients accrued CED >50 mSv and 4.5% (N = 14) accrued CED >100 mSv during ECMO. Over the entire hospitalization, 28% (N = 85) accrued >50 mSv and 14.7% (N = 45) accrued CED >100 mSv. Median CED during ECMO was 2.3 mSv (IQR, -0.82 to 8.1 mSv), and the entire hospitalization was 17.4 mSv (IQR, -4.5 to 56.6 mSv). Thirteen percent of the median CED accrued during hospitalization could be attributed to ECMO. Longer hospitalization was associated with a higher CED (50 days [IQR, -25 to 76 days] in CED >50 vs. 19 days [IQR, -10 to 32 days] in CED <50). Computer tomography (CT) scans and interventional radiology (IR) procedures contributed to 43.8% and 44.86%, respectively, of CED accrued on ECMO and 52.2% and 37.1% of CED accumulated during the whole hospitalization. Guidelines aimed at mitigating radiation exposure are urgently needed.

摘要

体外膜肺氧合(ECMO)会使患者接受多次影像学检查。我们假设 ECMO 患者所受的辐射暴露超过了国际辐射防护委员会(ICRP)的建议累积有效剂量(CED,>20mSv 和 5 年累积 CED 限值>100mSv)。我们在 2016 年 1 月至 2018 年 12 月期间在一家学术医疗中心进行了一项回顾性观察性研究,涉及 ECMO 成人住院患者(N=306)。我们从参考值计算出电离辐射,以确定 CED。大约有 9.4%(N=29)的患者在 ECMO 期间的 CED 超过 50mSv,4.5%(N=14)的患者的 CED 超过 100mSv。在整个住院期间,28%(N=85)的患者 CED 超过 50mSv,14.7%(N=45)的患者 CED 超过 100mSv。ECMO 期间的 CED 中位数为 2.3mSv(IQR,-0.82 至 8.1mSv),整个住院期间的 CED 中位数为 17.4mSv(IQR,-4.5 至 56.6mSv)。在住院期间,13%的 CED 中位数可归因于 ECMO。住院时间较长与 CED 较高相关(CED>50 为 50 天[IQR,-25 至 76 天],CED<50 为 19 天[IQR,-10 至 32 天])。CT 扫描和介入放射学(IR)程序分别占 ECMO 上累积的 CED 的 43.8%和 44.86%,以及整个住院期间累积的 CED 的 52.2%和 37.1%。急需制定旨在减少辐射暴露的指南。

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