饲粮甜菜碱改善夏季热应激生长兔的肠道健康和生产性能。
Dietary Betaine improves the intestinal health and growth performance of heat-stressed growing rabbits in summer.
机构信息
Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.
出版信息
J Anim Sci. 2023 Jan 3;101. doi: 10.1093/jas/skad363.
The main objective of this study is to explore how various amounts of Bet affect growth performance, nutritional digestibility, and intestinal health of growing rabbits under high-temperature environment in summer. A total of 150 healthy 35-d-old weaned QiXing meat rabbits (Germany White rabbit × Sichuan White rabbit) were individually assigned to five treatments, each with 30 replicates and one rabbit per replicate. The control group was fed with basal diet, while the experimental group received a basal diet supplemented with 0.75, 1.0, 1.5, and 2.0 g Bet/kg diet, respectively. During the whole experimental stage, all animals can eat and drink freely, and they were kept in the rabbit house with an average daily temperature of 30.11 ± 0.5 ℃ and a relative humidity of 71.02 ± 5.07%. The results showed that dietary supplementation with 1.5 g/kg Bet increased average daily gain and decreased feed to gain ratio from days 1 to 42 as compared to the control group (P < 0.05), adding 0.75, 1.0, 1.5, and 2.0 g/kg Bet increased average daily gain and average daily feed intake from days 22 to 42 (P < 0.05), and increased the nutritional digestibility of acid detergent fiber (P < 0.05). Furthermore, dietary supplementation with 1.0, 1.5, and 2.0 g/kg Bet reduced d-lactate content and diamine oxidase activity in the serum (P < 0.05). Compared to the control group, supplementation of 0.75 and 1.5 g/kg Bet improved glutathione peroxidase activities in the duodenum and ileum, adding 0.75, 1.0, 1.5, and 2.0 g/kg Bet decreased malonaldehyde content in the duodenum and jejunum (P < 0.05). Moreover, the supplement of 1.5 and 2.0 g/kg Bet upregulated JAM-2 and IL-10 levels in the jejunum (P < 0.05). In conclusion, supplementation with Bet in the diet improves the growth performance, nutrient digestibility, and intestinal health of growing rabbits under high-temperature environments, and the 1.5 g Bet/kg diet group has the best effect.
本研究的主要目的是探讨在夏季高温环境下，不同剂量的 Bet 对生长兔的生长性能、营养消化率和肠道健康的影响。将 150 只 35 日龄健康断奶麒麟肉兔（德国白兔×四川白兔）单独分配到 5 个处理组中，每个处理组有 30 个重复，每个重复 1 只兔。对照组饲喂基础日粮，实验组分别在基础日粮中添加 0.75、1.0、1.5 和 2.0 g/kg 日粮的 Bet。整个试验阶段，所有动物均可自由采食和饮水，饲养在平均日温为 30.11±0.5℃、相对湿度为 71.02±5.07%的兔舍中。结果表明，与对照组相比，日粮中添加 1.5 g/kg Bet 可提高第 1 天至第 42 天的平均日增重，降低料重比（P<0.05），添加 0.75、1.0、1.5 和 2.0 g/kg Bet 可提高第 22 天至第 42 天的平均日增重和平均日采食量（P<0.05），提高酸性洗涤纤维的营养消化率（P<0.05）。此外，日粮中添加 1.0、1.5 和 2.0 g/kg Bet 可降低血清中 d-乳酸含量和二胺氧化酶活性（P<0.05）。与对照组相比，添加 0.75 和 1.5 g/kg Bet 可提高十二指肠和回肠中的谷胱甘肽过氧化物酶活性，添加 0.75、1.0、1.5 和 2.0 g/kg Bet 可降低十二指肠和空肠中的丙二醛含量（P<0.05）。此外，添加 1.5 和 2.0 g/kg Bet 可上调空肠中 JAM-2 和 IL-10 的水平（P<0.05）。综上所述，日粮中添加 Bet 可提高高温环境下生长兔的生长性能、营养消化率和肠道健康，以 1.5 g Bet/kg 日粮组效果最佳。
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