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连续锯肌-肋间平面阻滞用于上腹部手术围手术期镇痛:一项前瞻性随机对照研究。

Continuous Serratus - Intercostal Plane Block for Perioperative Analgesia in Upper Abdominal Surgeries: A Prospective Randomized Controlled Study.

作者信息

Mamoun Mohamed A, Alrefaey Alrefaey K, Abo-Zeid Maha Ahmed

机构信息

Department of Anaesthesia and Surgical Intensive Care, Mansoura University, Mansoura, Egypt.

出版信息

Turk J Anaesthesiol Reanim. 2023 Oct 24;51(5):402-407. doi: 10.4274/TJAR.2023.231260.

DOI:10.4274/TJAR.2023.231260
PMID:37876166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10606739/
Abstract

OBJECTIVE

Acute pain management after open abdominal surgeries is an essential goal in perioperative management.. Recently, serratus-intercostal plane block (SIPB) was suggested as an analgesic technique for upper abdominal surgeries.

METHODS

This prospective, randomized, controlled study included sixty adult patients scheduled for open upper abdominal surgeries. Patients were allocated into two equal groups: SIPB group (S group, n = 30) and control group (the C group, n = 30). In the S group, SIPB was performed in the midaxillary line at the eighth rib level followed by continuous infusion of local anaesthetic for the first postoperative day. In the C group, no block was done. The primary objective of the study was to control postoperative pain on the first postoperative day as assessed by the numerical rating scale (NRS). Secondary outcomes included perioperative hemodynamics, total postoperative analgesic consumption, number of analgesic requests, and incidence of postoperative nausea and vomiting.

RESULTS

The mean postoperative NRS reported in group S was statistically lower than that in group C (2.4±0.7, 3.9±0.31, < 0.001). The postoperative morphine consumption was lower in the S group than in the C group [(0 (0-4), 3 (1-4), respectively, < 0.001]. The incidence of PONV was significantly lower in the S group than in the C group (16.7% and 40%, < 0.045).

CONCLUSION

SIPB was associated with a better analgesic profile compared with the control group after upper abdominal surgeries. Further studies are recommended to determine block safety in special patient groups, including bariatric and laparoscopic surgeries.

摘要

目的

开放性腹部手术后的急性疼痛管理是围手术期管理的一个重要目标。最近,有人提出锯齿肌-肋间平面阻滞(SIPB)作为上腹部手术的一种镇痛技术。

方法

这项前瞻性、随机对照研究纳入了60例计划进行开放性上腹部手术的成年患者。患者被分为两组,每组30例:SIPB组(S组)和对照组(C组)。在S组中,于腋中线第8肋水平进行SIPB,然后在术后第一天持续输注局部麻醉药。C组不进行阻滞。本研究的主要目的是通过数字评分量表(NRS)评估术后第一天的术后疼痛控制情况。次要结局包括围手术期血流动力学、术后总镇痛药物消耗量、镇痛需求次数以及术后恶心呕吐的发生率。

结果

S组报告的术后平均NRS在统计学上低于C组(分别为2.4±0.7、3.9±0.31,<0.001)。S组术后吗啡消耗量低于C组[分别为0(0 - 4)、3(1 - 4),<0.001]。S组术后恶心呕吐的发生率显著低于C组(分别为16.7%和40%,<0.045)。

结论

与对照组相比,上腹部手术后SIPB具有更好的镇痛效果。建议进一步研究以确定特殊患者群体(包括肥胖症和腹腔镜手术患者)的阻滞安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0f/10606739/c784037c51d4/TJAR-51-402-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0f/10606739/e6d0b8183e56/TJAR-51-402-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0f/10606739/5142d22ce5a9/TJAR-51-402-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0f/10606739/5bc69f04083c/TJAR-51-402-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0f/10606739/c784037c51d4/TJAR-51-402-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0f/10606739/e6d0b8183e56/TJAR-51-402-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0f/10606739/5142d22ce5a9/TJAR-51-402-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0f/10606739/5bc69f04083c/TJAR-51-402-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b0f/10606739/c784037c51d4/TJAR-51-402-g4.jpg

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本文引用的文献

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Current approaches to acute postoperative pain management after major abdominal surgery: a narrative review and future directions.重大腹部手术后急性疼痛管理的当前方法:叙述性综述与未来方向。
Br J Anaesth. 2022 Sep;129(3):378-393. doi: 10.1016/j.bja.2022.05.029. Epub 2022 Jul 6.
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Perioperative Opioids, the Opioid Crisis, and the Anesthesiologist.围手术期阿片类药物、阿片类药物危机与麻醉医生
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Serratus intercostal interfascial plane block in supraumbilical surgery: a prospective randomized comparison.腹上区手术中肋间神经筋膜平面阻滞:一项前瞻性随机对照研究。
Minerva Anestesiol. 2021 Feb;87(2):165-173. doi: 10.23736/S0375-9393.20.14882-X. Epub 2020 Dec 15.
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Interfascial Plane Blocks and Laparoscopic Abdominal Surgery: A Narrative Review.筋膜间平面阻滞与腹腔镜腹部手术:一项叙述性综述
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Anesth Analg. 2020 Aug;131(2):411-448. doi: 10.1213/ANE.0000000000004833.
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Is a Combination of the Serratus Intercostal Plane Block and Rectus Sheath Block Superior to the Bilateral Oblique Subcostal Transversus Abdominis Plane Block in Laparoscopic Cholecystectomy?在腹腔镜胆囊切除术中,锯齿状肋间平面阻滞联合腹直肌鞘阻滞是否优于双侧肋下斜行腹横肌平面阻滞?
Eurasian J Med. 2020 Feb;52(1):34-37. doi: 10.5152/eurasianjmed.2019.19048.
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Multimodal analgesia using intrathecal diamorphine, and paravertebral and rectus sheath catheters are as effective as thoracic epidural for analgesia post-open two-phase esophagectomy within an enhanced recovery program.在强化康复计划中,使用鞘内注射二氢吗啡酮、椎旁和腹直肌鞘导管的多模式镇痛与胸段硬膜外镇痛在开放性两阶段食管切除术后的镇痛效果相同。
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Serratus-intercostal interfascial block as an opioid-saving strategy in supra-umbilical open surgery.锯齿肌-肋间筋膜阻滞作为脐上开放手术中节省阿片类药物的策略。
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