Xie Yan, Wang Zhixue, Chen Zongtao
Health Management Centre, The First Affiliated Hospital of Army Medical University, Chongqing 400038, China.
Department of Clinical Laboratory, Bishan Hospital of Chongqing Medical University (Bishan Hospital of Chongqing), Chongqing 402760, China.
Int J Endocrinol. 2023 Oct 16;2023:5216945. doi: 10.1155/2023/5216945. eCollection 2023.
We analyzed the detection rates of metabolic syndrome (MetS) and subclinical thyroid dysfunction, including subclinical hyperthyroidism (SCHyper) and subclinical hypothyroidism (SCH), in healthy people, as well as their relationship. Clinical data were collected from 28,568 healthy individuals who underwent physical examinations. The detection rates of SCHyper, SCH, and MetS, as well as in different genders and ages, were analyzed. The detection rate of SCHyper and SCH in females was significantly higher than that in males ( < 0.001), but that of MetS in males was significantly higher than that in females ( < 0.001). In each age group, the detection rate of SCH in females was higher than that in males ( < 0.001). The detection rate of SCH was significantly different in different age groups ( < 0.001). The detection rates of hyperlipidemia ( < 0.001), obesity ( = 0.004), hypertension ( = 0.009), and hyperglycemia ( < 0.001) in the female SCH group were significantly higher than those in the normal group. The detection rates of hyperlipidemia ( = 0.006), obesity ( = 0.04), and hypertension ( = 0.04) in the male SCH group were higher than those in the normal group. The males with SCHyper were more prone to hyperlipidemia ( = 0.02) and obesity ( = 0.03). In addition, the female SCHyper group was not significantly different from the normal group ( > 0.05). Conclusively, the detection rate of SCHyper and SCH in females is higher than that in males, which increases with age. Attention should be paid to subclinical thyroid dysfunction in elderly people, especially females. Early individualized screening and early intervention should be carried out for people with abnormal metabolism.
我们分析了健康人群中代谢综合征（MetS）和亚临床甲状腺功能障碍（包括亚临床甲状腺功能亢进症（SCHyper）和亚临床甲状腺功能减退症（SCH））的检出率及其关系。收集了28568名接受体检的健康个体的临床资料。分析了SCHyper、SCH和MetS在不同性别和年龄中的检出率。女性中SCHyper和SCH的检出率显著高于男性（<0.001），但男性中MetS的检出率显著高于女性（<0.001）。在各年龄组中，女性SCH的检出率高于男性（<0.001）。不同年龄组中SCH的检出率有显著差异（<0.001）。女性SCH组中高脂血症（<0.001）、肥胖（=0.004）、高血压（=0.009）和高血糖（<0.001）的检出率显著高于正常组。男性SCH组中高脂血症（=0.006）、肥胖（=0.04）和高血压（=0.04）的检出率高于正常组。患有SCHyper的男性更容易患高脂血症（=0.02）和肥胖（=0.03）。此外，女性SCHyper组与正常组无显著差异（>0.05）。总之，女性中SCHyper和SCH的检出率高于男性，且随年龄增长而增加。老年人，尤其是女性，应注意亚临床甲状腺功能障碍。对于代谢异常的人群应进行早期个体化筛查和早期干预。
