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外周血管通路作为儿科重症监护病房的唯一通路模式。

Peripheral vascular access as exclusive access mode in pediatric intensive care unit.

作者信息

Armstrong Sonya Hayes, Gangu Shantaveer, West Alina Nico, Spentzas Thomas

机构信息

Pediatric Intensive Care Unit, Le Bonheur Children's Hospital, Memphis, TN, United States.

Division of Pediatric Critical Care Medicine, University of Tennessee Health Science Center, Memphis, TN, United States.

出版信息

Front Pediatr. 2023 Oct 9;11:1259395. doi: 10.3389/fped.2023.1259395. eCollection 2023.

Abstract

INTRODUCTION

The type of vascular access (central or peripheral) in pediatric critical care depends on several factors, including the duration of treatment, the properties of the medication (osmolarity or vesicant), and the need for central pressure monitoring. The utilization of peripheral intravascular catheters (PIVCs) has shown a notable increase in the number of patients being treated. Extended dwell or midline catheters are another peripheral access option in addition to PIVCs. However, there are currently no established guidelines on their placement.

OBJECTIVES

The aim of this study is to estimate the duration of dwell time for PIVCs, analyze the specific parameters affecting it, and develop recommendations for switching to extended dwell and midline catheter placement as an alternative to peripheral access.

METHODS

The study enrolled patients aged 0-18 years admitted to the pediatric intensive care unit (PICU) for over 24 h and managed with peripheral access only over 2 years (2019-2021).

MEASUREMENTS AND MAIN RESULTS

A total of 484 patients met the specified criteria. Patients who had peripheral access exhibited a lower PRISM score and a shorter length of stay in the PICU, with mean values of 18 (SD: 8.5) and 9.5 (SD: 6.4) days, respectively, compared with patients who had central access with mean values of 8.9 (SD: 5.9) and 5.7 (SD: 3.6) days, respectively. The PIVC dwell time was found to be 50.1 h (SD: 65.3) and required an average of 1.6 insertion attempts. Patients with three or more insertions exhibited an increased odds ratio of 5.2 (95% CI: 3.1-8.5) for receiving an extended dwell or midline insertion. Increased dwell time was associated with female gender, 59.5 h (< 0.001), first attempt insertion, 53.5 h (< 0.001), use of 24 Ga bore, 56.3 h (= 0.04), left-sided insertions, 54.9 (= 0.07), less agitation, 54.8 h (= 0.02), and less edema, 61.6 (< 0.001). Decreased dwell time was associated with the use of vancomycin infusion at 24.2 h (< 0.001) and blood transfusions at 29.3 h (< 0.001).

CONCLUSIONS

Extended catheters last longer than PIVCs in PICU patients. Extended catheter placement requires consideration of the length of treatment, as well as the overall body edema, the level of the patient's restlessness, and the need for vancomycin infusion or blood transfusions, as these factors reduce PIVC dwell time and expose the patients to painful insertions. For such cases, an extended dwell catheter may be a better option, even if the projected treatment time is less than 6 days.

摘要

引言

儿科重症监护中血管通路的类型(中心或外周)取决于多个因素,包括治疗持续时间、药物特性(渗透压或发泡剂)以及中心压力监测的需求。外周静脉内导管(PIVC)的使用在接受治疗的患者数量上有显著增加。除了PIVC外,延长留置或中线导管是另一种外周通路选择。然而,目前尚无关于其放置的既定指南。

目的

本研究的目的是估计PIVC的留置时间,分析影响其的具体参数,并制定关于转换为延长留置和中线导管放置作为外周通路替代方案的建议。

方法

该研究纳入了年龄在0至18岁之间、入住儿科重症监护病房(PICU)超过24小时且在两年(2019 - 2021年)内仅采用外周通路管理的患者。

测量与主要结果

共有484名患者符合指定标准。采用外周通路的患者PRISM评分较低,在PICU的住院时间较短,平均值分别为18(标准差:8.5)天和9.5(标准差:6.4)天,而采用中心通路的患者平均值分别为8.9(标准差:5.9)天和5.7(标准差:3.6)天。发现PIVC的留置时间为50.1小时(标准差:65.3),平均需要1.6次插入尝试。进行三次或更多次插入的患者接受延长留置或中线插入的比值比增加至5.2(95%置信区间:3.1 - 8.5)。留置时间增加与女性性别(59.5小时,<0.001)、首次尝试插入(53.5小时,<0.001)、使用24G规格(56.3小时,=0.04)、左侧插入(54.9小时,=0.07)、躁动较少(54.8小时,=0.02)以及水肿较少(61.6小时,<0.001)相关。留置时间减少与使用万古霉素输注(24.2小时,<0.001)和输血(29.3小时,<0.001)相关。

结论

在PICU患者中,延长导管的留置时间比PIVC长。延长导管放置需要考虑治疗时间、全身水肿程度、患者躁动水平以及万古霉素输注或输血的需求,因为这些因素会缩短PIVC的留置时间并使患者面临痛苦的插入操作。对于此类情况,即使预计治疗时间少于6天,延长留置导管可能也是更好的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b896/10591082/dbbc30671e30/fped-11-1259395-g001.jpg

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