Child Health Evaluative Sciences, The Research Institute Hospital for Sick Children, Toronto, Ontario, Canada.
Departments of Paediatrics and Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.
PLoS One. 2024 Oct 24;19(10):e0309650. doi: 10.1371/journal.pone.0309650. eCollection 2024.
Though 60-80% of hospitalized patients have an intravascular device placed during hospitalization, there is a substantial risk of complication related to the placement, maintenance and removal of these devices. The objectives of this study were to describe vascular access device use, device complications and lumen dysfunction.
An observational cohort study was conducted over a 4.5 years period, in two quaternary, university-affiliated paediatric intensive care units (ICU). Eligible patients were admitted to either the paediatric or cardiac ICU and had one or more vascular access devices in-situ at the time of enrolment. Vascular access devices were defined as any external connection directly into the circulation including peripheral and central veins, arteries or bone marrow. Consistent with practice in the studied ICUs removal of peripheral catheters was regarded as due to dysfunction or complication.
220 patients, 683 devices and 924 lumens were observed. The device complication rate was 21% and the lumen complication rate was 25%. The median duration without complication was 18 days for arterial catheters, 14 days for central venous catheters; 13 days for peripherally inserted central catheters and 4 days for peripheral intravenous catheters. On one third of all patient days, the volume of fluid administered to maintain VADs was equal to or greater than 20% of the total hourly total fluid intake.
Approximately 1 in 5 vascular devices had one or more complications in ICU, most devices continued to be used without removal, and some complications resolved. The implications of the fluids infused to maintain device function warrants further study, as do strategies to resolve or limit the their complications in children.
尽管 60-80%的住院患者在住院期间会放置血管内装置,但这些装置的放置、维护和移除存在相当大的并发症风险。本研究的目的是描述血管通路装置的使用、装置并发症和管腔功能障碍。
本研究为为期 4.5 年的观察性队列研究,在两家四级、大学附属儿科重症监护病房(PICU)进行。符合条件的患者被收入儿科或心脏 PICU,在入组时体内有一个或多个血管内装置。血管内装置定义为任何直接进入循环的外部连接,包括外周静脉和中心静脉、动脉或骨髓。与研究中 ICU 的实践一致,外周导管的移除被视为由于功能障碍或并发症。
共观察了 220 名患者、683 个装置和 924 个管腔。装置并发症发生率为 21%,管腔并发症发生率为 25%。无并发症的中位持续时间为动脉导管 18 天,中心静脉导管 14 天,外周中心静脉导管 13 天,外周静脉导管 4 天。在所有患者日的三分之一中,为维持 VAD 而输注的液体量等于或大于总每小时液体摄入量的 20%。
大约每 5 个血管装置中就有 1 个或多个在 ICU 发生并发症,大多数装置继续使用而不被移除,并且一些并发症得到解决。维持装置功能所输注的液体的影响值得进一步研究,以及解决或限制儿童并发症的策略。