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单层与双层移植物技术在鼓膜成形术中治疗鼓膜大部穿孔的对比研究

Comparative Study Between Single Layer and Double Layer Graft Technique in Tympanoplasty for Subtotal Tympanic Membrane Perforation.

作者信息

Aziz Ahmed Abdel Rahman Abdel, Hafez Montaser Abdel Salam, Mahmoud Ashraf Gamal, Hamad AbdelMoneim H

机构信息

Department of Otorhinolaryngology, Faculty of Medicine, El Minia university, Egypt.

出版信息

Int Arch Otorhinolaryngol. 2023 Mar 3;27(4):e667-e671. doi: 10.1055/s-0043-1761174. eCollection 2023 Oct.

DOI:10.1055/s-0043-1761174
PMID:37876686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10593524/
Abstract

Tympanoplasty is the main treatment of mucosal type of chronic suppurative otitis media.  The aim of the present study was to compare clinical outcomes in terms of healing and audiological outcomes of two groups. The authors used single layer graft (perichondrium with cartilage island) graft in one group and double layer grafts (perichondrium cartilage island composite plus temporalis fascia) were used in the second group.  Forty patients complained of chronic suppurative otitis media safe type with subtotal perforation subdivided into two groups. The first group author used single-layer perichondrium with cartilage island graft (composite graft) while in the second group authors used double graft in the form of perichondrium/cartilage island (composite graft) plus temporalis fascia.  There was no significant difference in the mean Air bone gap (ABG) between pre- and post-operative audiometry in subjects who had single layer tympanoplasty. There was a significant difference in the mean ABG between pre- and postoperative audiometry in subjects who had double layer tympanoplasty. There was a significant difference in in the mean ABG differences between subjects who had single layer tympanoplasty and double layer tympanoplasty. Also, there was a significant difference in the healing of the tympanic membrane between subjects who had single layer tympanoplasty and double layer tympanoplasty.  Tympanoplasty by double graft (temporalis fascia and tragal cartilage/perichondrium) achieved a considerable improvement in healing of the tympanic membrane ™ with lower risk for residual perforation or graft rejection.

摘要

鼓室成形术是黏膜型慢性化脓性中耳炎的主要治疗方法。本研究的目的是比较两组在愈合和听力结果方面的临床疗效。作者在一组中使用单层移植物(带软骨岛的软骨膜),在第二组中使用双层移植物(软骨膜软骨岛复合物加颞肌筋膜)。40例主诉为安全型慢性化脓性中耳炎伴部分穿孔的患者被分为两组。第一组作者使用带软骨岛的单层软骨膜移植物(复合移植物),而在第二组中作者使用软骨膜/软骨岛(复合移植物)加颞肌筋膜形式的双层移植物。接受单层鼓室成形术的受试者术前和术后听力测定的平均气骨导间距(ABG)之间无显著差异。接受双层鼓室成形术的受试者术前和术后听力测定的平均ABG之间存在显著差异。接受单层鼓室成形术和双层鼓室成形术的受试者之间的平均ABG差异存在显著差异。此外,接受单层鼓室成形术和双层鼓室成形术的受试者之间鼓膜愈合情况存在显著差异。双层移植物(颞肌筋膜和耳屏软骨/软骨膜)鼓室成形术在鼓膜愈合方面取得了相当大的改善,残余穿孔或移植物排斥风险较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0573/10593524/7ac866eb8097/10-1055-s-0043-1761174-i221315-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0573/10593524/c7065d2a37b0/10-1055-s-0043-1761174-i221315-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0573/10593524/5ae64bf00bf6/10-1055-s-0043-1761174-i221315-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0573/10593524/7ac866eb8097/10-1055-s-0043-1761174-i221315-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0573/10593524/c7065d2a37b0/10-1055-s-0043-1761174-i221315-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0573/10593524/5ae64bf00bf6/10-1055-s-0043-1761174-i221315-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0573/10593524/7ac866eb8097/10-1055-s-0043-1761174-i221315-3.jpg

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Eur Arch Otorhinolaryngol. 2022 Jan;279(1):181-186. doi: 10.1007/s00405-021-06668-x. Epub 2021 Feb 13.
2
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Pattern of tympanic membrane perforation in a tertiary hospital in Nigeria.
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Niger J Clin Pract. 2018 Aug;21(8):1044-1049. doi: 10.4103/njcp.njcp_380_17.
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