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清醒状态下单孔电视辅助胸腔镜手术用于一名晚期纵隔SMARCA4缺陷肿瘤患者广泛、感染性血胸的引流

Awake Uniportal VATS for the Evacuation of an Extensive, Superinfected Hemothorax in a Patient with Advanced Mediastinal SMARCA4-Deficient Tumor.

作者信息

Lobinger Dominik, Reiche Alicia, Hiebinger Andreas, Bodner Johannes

机构信息

Department of Thoracic Surgery, München Klinik Bogenhausen, Munchen, Germany.

出版信息

Thorac Cardiovasc Surg Rep. 2023 Oct 23;12(1):e54-e56. doi: 10.1055/a-2178-0485. eCollection 2023 Jan.

DOI:10.1055/a-2178-0485
PMID:37877100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10593520/
Abstract

The so-called nonintubated or awake video-assisted thoracoscopic surgery (NIVATS) is performed on spontaneously breathing patients, which was shown to reduce postoperative complications and shorten hospital stay.  Awake uniportal VATS was indicated for the evacuation of an extensive, superinfected hemothorax with symptomatic mediastinal shift in a patient with advanced mediastinal SMARCA4-deficient tumor and declined condition, who did not allow a general anesthetic procedure and was not a candidate for extensive surgery.  This short microinvasive intervention was a prerequisite to stabilize the threat to the patient's life and thus potentially enable any further tumor-specific therapy.

摘要

所谓的非插管或清醒电视辅助胸腔镜手术(NIVATS)是在自主呼吸的患者身上进行的,已证明该手术可减少术后并发症并缩短住院时间。清醒单孔胸腔镜手术适用于一名患有晚期纵隔SMARCA4缺陷肿瘤且病情恶化的患者,该患者出现广泛的、感染性血胸并伴有有症状的纵隔移位,不允许进行全身麻醉手术,也不适合进行广泛手术。这种简短的微创干预是稳定对患者生命威胁的先决条件,从而有可能使任何进一步的肿瘤特异性治疗成为可能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee27/10593520/a064190b6e79/10-1055-a-2178-0485-i0520230471crt-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee27/10593520/a064190b6e79/10-1055-a-2178-0485-i0520230471crt-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee27/10593520/a064190b6e79/10-1055-a-2178-0485-i0520230471crt-1.jpg

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本文引用的文献

1
The Anesthetic Management of Patients Undergoing Nonintubated Video-Assisted Thoracic Surgery.非插管电视辅助胸腔镜手术患者的麻醉管理
Curr Anesthesiol Rep. 2021;11(4):437-445. doi: 10.1007/s40140-021-00469-y. Epub 2021 Jul 16.
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Recent updates in thoracic SMARCA4-deficient undifferentiated tumor.胸部 SMARCA4 缺陷型未分化肿瘤的最新进展。
Semin Diagn Pathol. 2021 Sep;38(5):83-89. doi: 10.1053/j.semdp.2021.06.001. Epub 2021 Jun 4.
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Robotic-assisted Versus Video-assisted Thoracoscopic Lobectomy: Short-term Results of a Randomized Clinical Trial (RVlob Trial).
机器人辅助与电视辅助胸腔镜肺叶切除术:一项随机临床试验的短期结果(RVlob 试验)。
Ann Surg. 2022 Feb 1;275(2):295-302. doi: 10.1097/SLA.0000000000004922.
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Uniportal VATS for non-small cell lung cancer.单孔电视辅助胸腔镜手术治疗非小细胞肺癌
Gen Thorac Cardiovasc Surg. 2020 Jul;68(7):707-715. doi: 10.1007/s11748-019-01221-4. Epub 2019 Oct 15.
5
Non-intubated video-assisted thoracoscopic surgery intubated video-assisted thoracoscopic surgery for thoracic disease: a systematic review and meta-analysis of 1,684 cases.非插管电视辅助胸腔镜手术与插管电视辅助胸腔镜手术治疗胸部疾病:1684例病例的系统评价和荟萃分析
J Thorac Dis. 2019 Aug;11(8):3556-3568. doi: 10.21037/jtd.2019.07.48.
6
SMARCA4-deficient Thoracic Sarcomas: Clinicopathologic Study of 30 Cases With an Emphasis on Their Nosology and Differential Diagnoses.SMARCA4 缺陷性胸肉瘤:30 例临床病理研究,重点在于其分类学和鉴别诊断。
Am J Surg Pathol. 2019 Apr;43(4):455-465. doi: 10.1097/PAS.0000000000001188.
7
SMARCA4-deficient thoracic sarcoma: a distinctive clinicopathological entity with undifferentiated rhabdoid morphology and aggressive behavior.SMARCA4 缺陷性胸壁肉瘤:一种具有未分化横纹肌样形态和侵袭性行为的独特临床病理实体。
Mod Pathol. 2017 Oct;30(10):1422-1432. doi: 10.1038/modpathol.2017.61. Epub 2017 Jun 23.
8
SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas.SMARCA4 失活定义了一组未分化的胸恶性肿瘤,这些肿瘤在转录上与 BAF 缺陷型肉瘤相关。
Nat Genet. 2015 Oct;47(10):1200-5. doi: 10.1038/ng.3399. Epub 2015 Sep 7.