Afandiyeva Medina, Wu Xijue, Brennessel William W, Kadam Abhishek A, Kennedy C Rose
Department of Chemistry, University of Rochester, Rochester, NY 14627, USA.
Chem Commun (Camb). 2023 Nov 9;59(90):13450-13453. doi: 10.1039/d3cc04229d.
Herein, we describe nickel-catalyzed nitrile hydroboration with pinacolborane, wherein a tethered NHC-pyridonate ligand enables efficient catalysis (5 mol% [Ni], ≤6 h reaction time) at room temperature. Mechanistic studies, including isolation of the catalytically relevant intermediates, shed light on the cooperative role of the ligand in activating both reagents simultaneously.
在此，我们描述了镍催化的腈与频哪醇硼烷的硼氢化反应，其中一个连接的NHC-吡啶酮配体能够在室温下实现高效催化（5 mol% [Ni]，反应时间≤6小时）。机理研究，包括分离催化相关中间体，揭示了该配体在同时活化两种试剂方面的协同作用。
