Structural and Computational Biology, European Molecular Biology Laboratory, 69117, Heidelberg, Germany.
FEBS Lett. 2023 Nov;597(21):2599-2600. doi: 10.1002/1873-3468.14758. Epub 2023 Oct 25.
This graphical review provides a mechanistic overview of different molecular processes that are tightly coupled and cooperate to achieve efficient and spatial-temporally regulated co-transcriptional protein-RNA complex assembly, including co-transcriptional RNA folding, processing, modification and the assembly in context of biomolecular condensates.
这篇图形综述提供了一个机制概述,介绍了不同的分子过程是如何紧密偶联和协作,以实现高效和时空调节的共转录蛋白-RNA 复合物组装,包括共转录 RNA 折叠、加工、修饰以及在生物分子凝聚物背景下的组装。